Evidence map›Paper›PMID 37686389›Full record

ArticleInternational journal of molecular sciences2023

Evaluation of Anticancer and Anti-Inflammatory Activities of Some Synthetic Rearranged Abietanes.

Mustapha Ait El Had, Houda Zentar, Blanca Ruiz-Muñoz, Juan Sainz, Juan J Guardia, Antonio Fernández, José Justicia, Enrique Alvarez-Manzaneda, Fernando J Reyes-Zurita, Rachid Chahboun

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Mustapha Ait El HadDepartamento de Química Orgánica, Facultad de Ciencias, Instituto de Biotecnología, Universidad de Granada, 18071 Granada, Spain.ORCID 0000-0002-2619-8479
Houda ZentarDepartamento de Química Orgánica, Facultad de Ciencias, Instituto de Biotecnología, Universidad de Granada, 18071 Granada, Spain.ORCID 0000-0001-6816-7390
Blanca Ruiz-MuñozDepartamento de Bioquímica y Biología Molecular I, Facultad de Ciencias, Universidad de Granada, 18071 Granada, Spain.
Juan SainzDepartamento de Bioquímica y Biología Molecular I, Facultad de Ciencias, Universidad de Granada, 18071 Granada, Spain.ORCID 0000-0002-9355-2423
Juan J GuardiaDepartamento de Química Orgánica, Facultad de Ciencias, Instituto de Biotecnología, Universidad de Granada, 18071 Granada, Spain.
Antonio FernándezDepartamento de Química Orgánica, Facultad de Ciencias, Instituto de Biotecnología, Universidad de Granada, 18071 Granada, Spain.ORCID 0000-0001-9816-8482
José JusticiaDepartamento de Química Orgánica, Facultad de Ciencias, Instituto de Biotecnología, Universidad de Granada, 18071 Granada, Spain.ORCID 0000-0002-7712-0911
Enrique Alvarez-ManzanedaDepartamento de Química Orgánica, Facultad de Ciencias, Instituto de Biotecnología, Universidad de Granada, 18071 Granada, Spain.
Fernando J Reyes-ZuritaDepartamento de Bioquímica y Biología Molecular I, Facultad de Ciencias, Universidad de Granada, 18071 Granada, Spain.ORCID 0000-0003-3438-0753
Rachid ChahbounDepartamento de Química Orgánica, Facultad de Ciencias, Instituto de Biotecnología, Universidad de Granada, 18071 Granada, Spain.ORCID 0000-0001-5303-1183
Universidad de Granada · ES

Funding

Regional Government of Andalusia B-FQM-650-UGR-20the Junta de Andalucía - Universidad de Granada - European Regional Development B-FQM-278-UGR20
6 · The paper itself

Abstract

Synthesis of the rearranged abietane diterpenes pygmaeocins C and D, viridoquinone, saprorthoquinone, and 1-deoxyviroxocine has been successfully achieved. The anticancer and anti-inflammatory activities of selected orthoquinonic compounds

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsMelanoma, ExperimentalAbietanesAnimalsAnti-Inflammatory AgentsHT29 CellsHumansMiceAbietanesAnti-Inflammatory Agentsanti-inflammatory activityantitumor activityapoptosiscolorectal cancernitric oxiderearranged abietane typesemisynthesis

Identifiers

PMID37686389
PMCPMC10487843
OpenAlexW4386380097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.