Evidence map›Paper›PMID 37686333›Full record

ArticleInternational journal of molecular sciences2023

n-3 Polyunsaturated Fatty Acids Modulate LPS-Induced ARDS and the Lung-Brain Axis of Communication in Wild-Type versus Fat-1 Mice Genetically Modified for Leukotriene B4 Receptor 1 or Chemerin Receptor 23 Knockout.

Jessica Hernandez, Julia Schäffer, Christiane Herden, Fabian Johannes Pflieger, Sylvia Reiche, Svenja Körber, Hiromu Kitagawa, Joelle Welter, Susanne Michels, Carsten Culmsee and 6 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 3 countries.

Jessica HernandezInstitute of Veterinary Physiology and Biochemistry, Justus Liebig University Giessen, 35392 Giessen, Germany.
Julia SchäfferInstitute of Veterinary Physiology and Biochemistry, Justus Liebig University Giessen, 35392 Giessen, Germany.
Christiane HerdenInstitute of Veterinary Pathology, Justus Liebig University Giessen, 35392 Giessen, Germany.ORCID 0000-0003-1858-2267
Fabian Johannes PfliegerInstitute of Veterinary Physiology and Biochemistry, Justus Liebig University Giessen, 35392 Giessen, Germany.
Sylvia ReicheExcellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus Liebig University Giessen, 35392 Giessen, Germany.
Svenja KörberInstitute of Veterinary Pathology, Justus Liebig University Giessen, 35392 Giessen, Germany.
Hiromu KitagawaDepartment of Biomedical Engineering, Osaka Institute of Technology, Omiya, Osaka 535-8585, Japan.
Joelle WelterInstitute of Veterinary Physiology and Biochemistry, Justus Liebig University Giessen, 35392 Giessen, Germany.
Susanne MichelsInstitute of Pharmacology and Clinical Pharmacy, Philipps University of Marburg, 35032 Marburg, Germany.
Carsten CulmseeInstitute of Pharmacology and Clinical Pharmacy, Philipps University of Marburg, 35032 Marburg, Germany.ORCID 0000-0002-5121-5015
Jens BierExcellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus Liebig University Giessen, 35392 Giessen, Germany.
Natascha SommerExcellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus Liebig University Giessen, 35392 Giessen, Germany.
Jing X KangLaboratory for Lipid Medicine and Technology, Department of Medicine, Massachusetts General Hospital and Harvard Medical, Boston, MA 02129, USA.
Konstantin MayerDepartment of Internal Medicine, Justus Liebig University Giessen, 35392 Giessen, Germany.ORCID 0000-0002-6565-2187
Matthias HeckerExcellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus Liebig University Giessen, 35392 Giessen, Germany.
Christoph RummelInstitute of Veterinary Physiology and Biochemistry, Justus Liebig University Giessen, 35392 Giessen, Germany.ORCID 0000-0001-5457-4390
Justus-Liebig-Universität Gießen · DEPhilipps University of Marburg · DEMassachusetts General Hospital · USOsaka Institute of Technology · JP

Funding

EU Joint Programme - Neurodegenerative Disease Research (JPND) SOLID JPND2021-650-233Federal Ministry of Education and Research 01ED2207Research Campus Mid-Hessen Flexifunds 2021_3_1_2_HerdenUniversity of Giessen APC funds
6 · The paper itself

Abstract

Specialized pro-resolving mediators (SPMs) and especially Resolvin E1 (RvE1) can actively terminate inflammation and promote healing during lung diseases such as acute respiratory distress syndrome (ARDS). Although ARDS primarily affects the lung, many ARDS patients also develop neurocognitive impairments. To investigate the connection between the lung and brain during ARDS and the therapeutic potential of SPMs and its derivatives,

Indexed as

Fatty Acids, Omega-3Respiratory Distress SyndromeAnimalsBrainCadherinsChromatography, LiquidInflammationLipopolysaccharidesLungMiceMice, KnockoutReceptors, ChemokineReceptors, Leukotriene B4Tandem Mass SpectrometryCadherinsCMKLR1 protein, mousefat1 protein, mouseFatty Acids, Omega-3LipopolysaccharidesLtb4r1 protein, mouseReceptors, ChemokineReceptors, Leukotriene B4acute respiratory distress syndromecytokinesimmune-to-brain communicationlipid mediatorslipopolysaccharidelung–brain axisomega-3 fatty acidsresolvin E1 receptors

Identifiers

PMID37686333
PMCPMC10487657
OpenAlexW4386328163

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.