Evidence map›Paper›PMID 37686321›Full record

ArticleInternational journal of molecular sciences2023

Studying the Interaction between Bendamustine and DNA Molecule with SERS Based on AuNPs/ZnCl

Lina Yao, Yanjie Li, Zhenzhong Zuo, Ziyi Gong, Jie Zhu, Xiaoqiang Feng, Dan Sun, Kaige Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lina YaoState Key Laboratory of Cultivation Base for Photoelectric Technology and Functional Materials, National Center for International Research of Photoelectric Technology & Nano-Functional Materials and Application, Key Laboratory of Photoelectronic Technology of Shaanxi Province, Institute of Photonics and Photon-Technology, Northwest University, Xi'an 710127, China.
Yanjie LiState Key Laboratory of Cultivation Base for Photoelectric Technology and Functional Materials, National Center for International Research of Photoelectric Technology & Nano-Functional Materials and Application, Key Laboratory of Photoelectronic Technology of Shaanxi Province, Institute of Photonics and Photon-Technology, Northwest University, Xi'an 710127, China.
Zhenzhong ZuoState Key Laboratory of Cultivation Base for Photoelectric Technology and Functional Materials, National Center for International Research of Photoelectric Technology & Nano-Functional Materials and Application, Key Laboratory of Photoelectronic Technology of Shaanxi Province, Institute of Photonics and Photon-Technology, Northwest University, Xi'an 710127, China.
Ziyi GongState Key Laboratory of Cultivation Base for Photoelectric Technology and Functional Materials, National Center for International Research of Photoelectric Technology & Nano-Functional Materials and Application, Key Laboratory of Photoelectronic Technology of Shaanxi Province, Institute of Photonics and Photon-Technology, Northwest University, Xi'an 710127, China.
Jie ZhuState Key Laboratory of Cultivation Base for Photoelectric Technology and Functional Materials, National Center for International Research of Photoelectric Technology & Nano-Functional Materials and Application, Key Laboratory of Photoelectronic Technology of Shaanxi Province, Institute of Photonics and Photon-Technology, Northwest University, Xi'an 710127, China.
Xiaoqiang FengState Key Laboratory of Cultivation Base for Photoelectric Technology and Functional Materials, National Center for International Research of Photoelectric Technology & Nano-Functional Materials and Application, Key Laboratory of Photoelectronic Technology of Shaanxi Province, Institute of Photonics and Photon-Technology, Northwest University, Xi'an 710127, China.
Dan SunState Key Laboratory of Cultivation Base for Photoelectric Technology and Functional Materials, National Center for International Research of Photoelectric Technology & Nano-Functional Materials and Application, Key Laboratory of Photoelectronic Technology of Shaanxi Province, Institute of Photonics and Photon-Technology, Northwest University, Xi'an 710127, China.ORCID 0000-0002-9973-608X
Kaige WangState Key Laboratory of Cultivation Base for Photoelectric Technology and Functional Materials, National Center for International Research of Photoelectric Technology & Nano-Functional Materials and Application, Key Laboratory of Photoelectronic Technology of Shaanxi Province, Institute of Photonics and Photon-Technology, Northwest University, Xi'an 710127, China.
Northwest University · CN

Funding

National Key Scientific Instrument and Equipment Development Projects of China 51927804National Natural Science Foundation of China 61775181,61378083Natural Science Basic Research Program of Shaanxi Province-Major Basic Research Project 2016ZDJC-15, S2018-ZC-TD-0061State Key Laboratory of Transient Optics and Photonics, Chinese Academy of Sciences SKLST202109the foundation of Shaanxi International Science and Technology Cooperation 2016KW040
6 · The paper itself

Abstract

Bendamustine (BENDA) is a bifunctional alkylating agent with alkylating and purinergic antitumor activity, which exerts its anticancer effects by direct binding to DNA, but the detailed mechanism of BENDA-DNA interaction is poorly understood. In this paper, the interaction properties of the anticancer drug BENDA with calf thymus DNA (ctDNA) were systematically investigated based on surface-enhanced Raman spectroscopy (SERS) technique mainly using a novel homemade AuNPs/ZnCl

Indexed as

GoldMetal NanoparticlesBendamustine HydrochlorideDNAMolecular Docking SimulationSpectrum Analysis, RamanBendamustine HydrochlorideDNAGoldbendamustinecalf thymus DNAdrug–DNA interactionsolid-state substratesurface-enhanced Raman spectroscopy

Identifiers

PMID37686321
PMCPMC10487454
OpenAlexW4386307434

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.