Evidence map›Paper›PMID 37686294›Full record

ArticleInternational journal of molecular sciences2023

Impact of Developmental Changes of GABA

Linda Patt, Dario Tascio, Catia Domingos, Aline Timmermann, Ronald Jabs, Christian Henneberger, Christian Steinhäuser, Gerald Seifert

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Super-resolution Analysis of Astrocyte Morphology Using Expansion Microscopy.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  3. Article
  4. Review
  5. Transcriptional and bioinformatic analysis of GABAFrontiers in molecular neuroscience · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Linda PattInstitute of Cellular Neurosciences, Medical Faculty, University of Bonn, 53127 Bonn, Germany.
Dario TascioInstitute of Cellular Neurosciences, Medical Faculty, University of Bonn, 53127 Bonn, Germany.ORCID 0009-0004-0755-4476
Catia DomingosInstitute of Cellular Neurosciences, Medical Faculty, University of Bonn, 53127 Bonn, Germany.
Aline TimmermannInstitute of Cellular Neurosciences, Medical Faculty, University of Bonn, 53127 Bonn, Germany.
Ronald JabsInstitute of Cellular Neurosciences, Medical Faculty, University of Bonn, 53127 Bonn, Germany.ORCID 0000-0001-6612-7678
Christian HennebergerInstitute of Cellular Neurosciences, Medical Faculty, University of Bonn, 53127 Bonn, Germany.ORCID 0000-0002-5391-7387
Christian SteinhäuserInstitute of Cellular Neurosciences, Medical Faculty, University of Bonn, 53127 Bonn, Germany.ORCID 0000-0003-2579-8357
Gerald SeifertInstitute of Cellular Neurosciences, Medical Faculty, University of Bonn, 53127 Bonn, Germany.
University of Bonn · DE

Funding

Deutsche Forschungsgemeinschaft HE6949/1Deutsche Forschungsgemeinschaft HE6949/3Deutsche Forschungsgemeinschaft SE774/6Deutsche Forschungsgemeinschaft STE552/5
6 · The paper itself

Abstract

NG2 glia receive synaptic input from neurons, but the functional impact of this glial innervation is not well understood. In the developing cerebellum and somatosensory cortex the GABAergic input might regulate NG2 glia differentiation and myelination, and a switch from synaptic to extrasynaptic neuron-glia signaling was reported in the latter region. Myelination in the hippocampus is sparse, and most NG2 glia retain their phenotype throughout adulthood, raising the question of the properties and function of neuron-NG2 glia synapses in that brain region. Here, we compared spontaneous and evoked GABA

Indexed as

Receptors, GABA-AAnimalsChondroitin Sulfate Proteoglycan 4gamma-Aminobutyric AcidHippocampusInterneuronsMiceNeurogliaChondroitin Sulfate Proteoglycan 4gamma-Aminobutyric AcidReceptors, GABA-Aexpansion microscopyextrasynaptic receptorsGABAA receptorsgephyrinhippocampusneuron–glia interactionNG2 gliapostnatal developmentradixin

Identifiers

PMID37686294
PMCPMC10488269
OpenAlexW4386325753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.