Evidence map›Paper›PMID 37686161›Full record

ArticleInternational journal of molecular sciences2023

Dimethyl Fumarate Used as an Effective Treatment for Granuloma Annulare Disseminatum: An Immunohistochemical Case Study.

Max Gabutti, Kristine Heidemeyer, S Morteza Seyed Jafari, Simon Bossart, Robert E Hunger, Laurence Feldmeyer, Nikhil Yawalkar

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Max GabuttiDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.
Kristine HeidemeyerDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0001-9217-6086
S Morteza Seyed JafariDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.
Simon BossartDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.
Robert E HungerDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.
Laurence FeldmeyerDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.
Nikhil YawalkarDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0003-0024-338X
University of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This investigation demonstrates the use of dimethyl fumarate (DMF) for the treatment of disseminated granuloma annulare (GAD), a rare and chronic inflammatory skin disease. In this case, progressive GAD was treated with DMF, resulting in significant improvement of skin lesions within 5 weeks and complete healing within 7 months. Clinical response was associated with a reduction in inflammatory cells, including both T cell subsets (CD4+ > CD8+), CD183

Indexed as

DermatitisGranuloma AnnulareDimethyl FumarateHumansRare DiseasesSkinTreatment OutcomeDimethyl Fumaratedimethyl fumarategranuloma annulare disseminatuminflammatory cells

Identifiers

PMID37686161
PMCPMC10487489
OpenAlexW4386255064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.