Evidence map›Paper›PMID 37686076›Full record

ArticleInternational journal of molecular sciences2023

Photocatalytic and Photothermal Antimicrobial Mussel-Inspired Nanocomposites for Biomedical Applications.

Luis F Soto-Garcia, Ingrid D Guerrero-Rodriguez, Luu Hoang, Samantha Lauren Laboy-Segarra, Ngan T K Phan, Enrique Villafuerte, Juhyun Lee, Kytai T Nguyen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luis F Soto-GarciaDepartment of Bioengineering, The University of Texas at Arlington, Arlington, TX 76010, USA.ORCID 0000-0003-2967-0502
Ingrid D Guerrero-RodriguezDepartment of Bioengineering, The University of Texas at Arlington, Arlington, TX 76010, USA.ORCID 0000-0003-2190-3439
Luu HoangDepartment of Bioengineering, The University of Texas at Arlington, Arlington, TX 76010, USA.
Samantha Lauren Laboy-SegarraDepartment of Bioengineering, The University of Texas at Arlington, Arlington, TX 76010, USA.
Ngan T K PhanDepartment of Bioengineering, The University of Texas at Arlington, Arlington, TX 76010, USA.
Enrique VillafuerteDepartment of Bioengineering, The University of Texas at Arlington, Arlington, TX 76010, USA.
Juhyun LeeDepartment of Bioengineering, The University of Texas at Arlington, Arlington, TX 76010, USA.ORCID 0000-0002-9609-4376
Kytai T NguyenDepartment of Bioengineering, The University of Texas at Arlington, Arlington, TX 76010, USA.

Funding

Novel nanoparticles to stimulate therapeutic angiogenesis in peripheral arterial diseaseR01HL158204 · NHLBI · UNIVERSITY OF TEXAS ARLINGTON · PI LIU, LI, NGUYEN, KYTAI TRUONG · 2022 to 2025
$2.2M
High spatiotemporal optical imaging to study dynamics of 3D cell motion and behavior in living organismsR35GM150947 · NIGMS · UNIVERSITY OF TEXAS ARLINGTON · PI Juhyun Lee · 2023 to 2026
$1.5M
Interdisciplinary Training in Nanotechnology for Cardiovascular and Lung Diseases in North TexasT32HL134613 · NHLBI · UNIVERSITY OF TEXAS ARLINGTON · PI NGUYEN, KYTAI TRUONG · 2017 to 2021
$1.1M
Synergistic Upregulation of EpoR /RopE NPs for Enhancing Effective Angiogenesis to treat PADR15HL156076 · NHLBI · UNIVERSITY OF TEXAS ARLINGTON · PI NGUYEN, KYTAI TRUONG · 2021 to 2021
$443k
A nanocoating for continuous disinfection of frequently touched surfacesF31AI169954 · NIAID · UNIVERSITY OF TEXAS ARLINGTON · PI SOTO GARCIA, LUIS FERNANDO · 2022 to 2024
$72k
NHLBI NIH HHS R01 HL158204NHLBI NIH HHS R15 HL156076NHLBI NIH HHS T32 HL134613NIAID NIH HHS F31 AI169954NIGMS NIH HHS R35 GM150947NIH HHS F31 AI169954NIH HHS R01 HL158204NIH HHS R15 HL156076NIH HHS T32 HL134613
6 · The paper itself

Abstract

Bacterial infection has traditionally been treated with antibiotics, but their overuse is leading to the development of antibiotic resistance. This may be mitigated by alternative approaches to prevent or treat bacterial infections without utilization of antibiotics. Among the alternatives is the use of photo-responsive antimicrobial nanoparticles and/or nanocomposites, which present unique properties activated by light. In this study, we explored the combined use of titanium oxide and polydopamine to create nanoparticles with photocatalytic and photothermal antibacterial properties triggered by visible or near-infrared light. Furthermore, as a proof-of-concept, these photo-responsive nanoparticles were combined with mussel-inspired catechol-modified hyaluronic acid hydrogels to form novel light-driven antibacterial nanocomposites. The materials were challenged with models of Gram-negative and Gram-positive bacteria. For visible light, the average percentage killed (PK) was 94.6 for

Indexed as

Anti-Infective AgentsNanocompositesAnti-Bacterial AgentsEscherichia coliInfrared RaysStaphylococcus aureusAnti-Bacterial AgentsAnti-Infective Agentsantimicrobialnanocompositesphotocatalyticphotothermalpolydopaminetitanium oxide

Identifiers

PMID37686076
PMCPMC10488035

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.