Evidence map›Paper›PMID 37686014›Full record

ArticleInternational journal of molecular sciences2023

CRISPR-Cas9 Library Screening Identifies Novel Molecular Vulnerabilities in

Pauline Schneider, Priscilla Wander, Susan T C J M Arentsen-Peters, Kirsten S Vrenken, Dedeke Rockx-Brouwer, Fabienne R S Adriaanse, Veerle Hoeve, Irene Paassen, Jarno Drost, Rob Pieters and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Infant Acute Lymphoblastic Leukemia-New Therapeutic Opportunities.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Pauline SchneiderPrincess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.ORCID 0000-0003-0162-9436
Priscilla WanderPrincess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.
Susan T C J M Arentsen-PetersPrincess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.
Kirsten S VrenkenPrincess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.
Dedeke Rockx-BrouwerPrincess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.
Fabienne R S AdriaansePrincess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.
Veerle HoevePrincess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.
Irene PaassenPrincess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.
Jarno DrostPrincess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.
Rob PietersPrincess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.
Ronald W StamPrincess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.
Princess Máxima Center · NLOncode Institute · NL

Funding

Foundation KiKa Not applicable
6 · The paper itself

Abstract

In acute lymphoblastic leukemia (ALL), chromosomal translocations involving the

Indexed as

CRISPR-Cas SystemsPrecursor Cell Lymphoblastic Leukemia-LymphomaAntigens, NeoplasmCell LineGene LibraryHumansNeoplasm ProteinsTranscription FactorsAntigens, NeoplasmARID4B protein, humanNeoplasm ProteinsTranscription FactorsARID4BBMPR2CRISPR-Cas9epigenomeinfantkinomeKMT2A-rearrangedleukemiaMBD3

Identifiers

PMID37686014
PMCPMC10487613
OpenAlexW4386161822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.