Evidence map›Paper›PMID 37685884›Full record

ArticleInternational journal of molecular sciences2023

Real-World Data on Combined EGFR-TKI and Crizotinib Treatment for Acquired and De Novo

Edyta M Urbanska, Morten Grauslund, Peter R Koffeldt, Sarah L B Truelsen, Johan O Löfgren, Junia C Costa, Linea C Melchior, Jens B Sørensen, Eric Santoni-Rugiu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. TargetingTranslational lung cancer research · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. ALK-tyrosine kinase inhibitor intrinsic resistance due toTranslational lung cancer research · 2024
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Edyta M UrbanskaDepartment of Oncology, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark.ORCID 0000-0002-4578-9346
Morten GrauslundDepartment of Pathology, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark.
Peter R KoffeldtDepartment of Pathology, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark.ORCID 0009-0005-0193-650X
Sarah L B TruelsenDepartment of Pathology, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark.
Johan O LöfgrenDepartment of Clinical Physiology and Nuclear Medicine, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark.
Junia C CostaDepartment of Radiology, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark.
Linea C MelchiorDepartment of Pathology, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark.
Jens B SørensenDepartment of Oncology, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark.ORCID 0000-0001-7780-0178
Eric Santoni-RugiuDepartment of Pathology, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark.ORCID 0000-0002-2283-3535
Copenhagen University Hospital · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amplification of the

Indexed as

Lung NeoplasmsTyrosine Kinase InhibitorsCrizotinibErbB ReceptorsHumansIn Situ Hybridization, FluorescenceProto-Oncogene Proteins c-metCrizotinibEGFR protein, humanErbB ReceptorsProto-Oncogene Proteins c-metTyrosine Kinase Inhibitorsacquired MET amplificationcombined targeted therapyCrizotinibde novo MET amplificationEGFR-mutated NSCLCEGFR-TKI

Identifiers

PMID37685884
PMCPMC10487649
OpenAlexW4386092028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.