Evidence map›Paper›PMID 37685838›Full record

ArticleInternational journal of molecular sciences2023

The Functional Role of Myogenin in Cardiomyoblast H9c2 Cells Treated with High Glucose and Palmitic Acid: Insights into No-Rejection Heart Transplantation.

Po-Shun Hsu, Shu-Ting Liu, Yi-Lin Chiu, Chien-Sung Tsai

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Cells · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Po-Shun HsuGraduate Institute of Medical Sciences, National Defense Medical Center, Taipei 114, Taiwan.
Shu-Ting LiuDepartment of Biochemistry, National Defense Medical Center, Taipei 114, Taiwan.
Yi-Lin ChiuDepartment of Biochemistry, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0002-1827-6924
Chien-Sung TsaiGraduate Institute of Medical Sciences, National Defense Medical Center, Taipei 114, Taiwan.
National Defense Medical Center · TWTri-Service General Hospital · TW

Funding

National Science and Technology Council, Taiwan NSTC-112-2314-B-016-052 to P-S HsuTri-Service General Hospital, Taiwan TSGH-A-112007 to P-S Hsu
6 · The paper itself

Abstract

Various pathological alterations, including lipid-deposition-induced comparative cardiac lipotoxicity, contribute to cardiac aging in the failing heart. A decline in endogenous myogenin proteins can lead to the reversal of muscle cell differentiation and the creation of mononucleated muscle cells. Myogenin may be a specific regulator of adaptive responses to avoid pathological hypertrophy in the heart. Hence, it is important to understand the regulation of myogenin expression and functions in response to exposure to varied stresses. In this study, we first examined and verified the cytotoxic effect of palmitic acid on H9c2 cells. The reduction in

Indexed as

Heart TransplantationPalmitic AcidDoxorubicinHeartMyogeninDoxorubicinmethoxy-morpholinyl-doxorubicinMyogeninPalmitic Acidcell differentiationmyogeninpalmitic acidreactive oxygen speciestransplantation

Identifiers

PMID37685838
PMCPMC10487901
OpenAlexW4386049882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.