Evidence map›Paper›PMID 37685628›Full record

ReviewJournal of clinical medicine2023

Role of Cardiovascular Imaging in Risk Assessment: Recent Advances, Gaps in Evidence, and Future Directions.

Francesco Perone, Marco Bernardi, Alban Redheuil, Dario Mafrica, Edoardo Conte, Luigi Spadafora, Fiona Ecarnot, Lale Tokgozoglu, Carlos G Santos-Gallego, Sergio Emanuel Kaiser and 9 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
16.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Methods to assess atherosclerotic cardiovascular risk in chronic respiratory diseases: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  2. AI-driven multimodal retinal imaging for early detection and risk stratification of vascular and neurodegenerative diseases.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Review
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  19. Advancing cardiovascular risk assessment.Cardiovascular research · 2025
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 15 institutions in 8 countries.

Francesco PeroneCardiac Rehabilitation Unit, Rehabilitation Clinic "Villa delle Magnolie", Castel Morrone, 81020 Caserta, Italy.ORCID 0000-0002-1418-7908
Marco BernardiDepartment of Clinical, Internal Medicine, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0001-9269-8829
Alban RedheuilLaboratoire d'Imagerie Biomédicale, Sorbonne University, INSERM 1146, CNRS 7371, 75005 Paris, France.
Dario MafricaDepartment of Clinical, Internal Medicine, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, 00185 Rome, Italy.
Edoardo ConteCardiology Department, Galeazzi-Sant'Ambrogio Hospital IRCCS, 20100 Milan, Italy.ORCID 0000-0003-1443-5788
Luigi SpadaforaDepartment of Clinical, Internal Medicine, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0001-6443-4121
Fiona EcarnotDepartment of Cardiology, University Hospital Besancon, University of Franche-Comté, 25000 Besancon, France.ORCID 0000-0002-4224-9731
Lale TokgozogluDepartment of Cardiology, Medical Faculty, Hacettepe University, 06230 Ankara, Turkey.
Carlos G Santos-GallegoAtherothrombosis Research Unit, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0003-1408-8958
Sergio Emanuel KaiserDiscipline of Clinical and Experimental Pathophysiology, Rio de Janeiro State University, Rio de Janeiro 23070-200, Brazil.ORCID 0000-0003-0904-8564
Federica FogacciHypertension and Cardiovascular Risk Research Group, Medical and Surgical Sciences Department, Alma Mater Studiorum University of Bologna, 40126 Bologna, Italy.ORCID 0000-0001-7853-0042
Annabelle SabouretGustave-Roussy Institute, Hérault Department, 94805 Villejuif, France.
Deepak L BhattMount Sinai Heart, Icahn School of Medicine at Mount Sinai Health System, New York, NY 10029, USA.ORCID 0000-0002-1278-6245
Francesco PaneniDepartment of Cardiology, University Heart Center, University Hospital Zurich, 8091 Zurich, Switzerland.
Maciej BanachDepartment of Preventive Cardiology and Lipidology, Medical University of Lodz (MUL), Rzgowska 281/289, 93-338 Lodz, Poland.ORCID 0000-0001-6690-6874
Raul SantosHeart Institute, University of Sao Paulo Medical School, São Paulo 05403-903, Brazil.
Giuseppe Biondi ZoccaiDepartment of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 00185 Roma, Italy.ORCID 0000-0001-6103-8510
Kausik K RayImperial Centre for Cardiovascular Disease Prevention and Imperial Clinical Trials Unit, Department of Public Health and Primary Care, Imperial College London, London SW7 2BX, UK.
Pierre SabouretHeart Institute, Cardiology Department, Paris and National College of French Cardiologists, Pitié-Salpétrière Hospital, Sorbonne University, 75013 Paris, France.ORCID 0000-0002-0243-3673
Sapienza University of Rome · ITMount Sinai Health System · USCentre National de la Recherche Scientifique · FRClinica Mediterranea · ITHacettepe University · TRImperial College London · GBInstitut Gustave Roussy · FRIstituto Clinico Sant'Ambrogio · ITMedical University of Lodz · PLSorbonne Université · FRUniversidade de São Paulo · BRUniversidade do Estado do Rio de Janeiro · BRUniversité de franche-comté · FRUniversity of Bologna · ITUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optimal risk assessment for primary prevention remains highly challenging. Recent registries have highlighted major discrepancies between guidelines and daily practice. Although guidelines have improved over time and provide updated risk scores, they still fail to identify a significant proportion of at-risk individuals, who then miss out on effective prevention measures until their initial ischemic events. Cardiovascular imaging is progressively assuming an increasingly pivotal role, playing a crucial part in enhancing the meticulous categorization of individuals according to their risk profiles, thus enabling the customization of precise therapeutic strategies for patients with increased cardiovascular risks. For the most part, the current approach to patients with atherosclerotic cardiovascular disease (ASCVD) is homogeneous. However, data from registries (e.g., REACH, CORONOR) and randomized clinical trials (e.g., COMPASS, FOURIER, and ODYSSEY outcomes) highlight heterogeneity in the risks of recurrent ischemic events, which are especially higher in patients with poly-vascular disease and/or multivessel coronary disease. This indicates the need for a more individualized strategy and further research to improve definitions of individual residual risk, with a view of intensifying treatments in the subgroups with very high residual risk. In this narrative review, we discuss advances in cardiovascular imaging, its current place in the guidelines, the gaps in evidence, and perspectives for primary and secondary prevention to improve risk assessment and therapeutic strategies using cardiovascular imaging.

Indexed as

cardiovascular imagingcardiovascular riskpreventionrisk assessment

Identifiers

PMID37685628
PMCPMC10487991
OpenAlexW4386220061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.