Evidence map›Paper›PMID 37685597›Full record

ArticleJournal of clinical medicine2023

Long and Short-Term Effects of Hypothermic Machine Perfusion vs. Cold Storage on Transplanted Kidneys from Expanded Criteria Donors-A Matched Comparison Study.

Matthias Axelsson, Per Lindnér, Nils-Gunnar Pehrsson, Seema Baid-Agrawal

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matthias AxelssonTransplant Institute, Sahlgrenska Academy at the University of Gothenburg and Sahlgrenska University Hospital, 41345 Gothenburg, Sweden.ORCID 0009-0007-1674-6914
Per LindnérTransplant Institute, Sahlgrenska Academy at the University of Gothenburg and Sahlgrenska University Hospital, 41345 Gothenburg, Sweden.
Nils-Gunnar PehrssonStatistiska Konsultgruppen, 41463 Gothenburg, Sweden.
Seema Baid-AgrawalTransplant Institute, Sahlgrenska Academy at the University of Gothenburg and Sahlgrenska University Hospital, 41345 Gothenburg, Sweden.ORCID 0000-0001-8192-1079

Funding

Sahlgrenska University Hospital SU-ALF 75490
6 · The paper itself

Abstract

Hypothermic machine perfusion (HMP) has been shown to reduce delayed graft function (DGF)-rates in kidneys from expanded criteria donors (ECD) and may increase graft survival compared with static cold storage (SCS). This single-center, retrospective observational study aimed to evaluate this effect. The primary endpoint was the DGF-rate, defined as the use of dialysis in the first postoperative week, excluding the first 24 h. The main secondary endpoint was graft survival at 5 years. Recipients of ECD-kidneys between 2013 and 2021 with ≤2 grafts were included (n = 438). The SCS-kidneys were marginal-matched by propensity score to the HMP-group for donor age, cold ischemia time, and graft number. Multivariable adjusted analysis for confounders in the unmatched cohort and caliper-based ID-matching constituted sensitivity analyses. HMP showed a trend to lower DGF-rate in the marginal-matched comparison (9.2% vs. 16.1%,

Indexed as

delayed graft functionexpanded criteria donorgraft functiongraft survivalhypothermic machine perfusionkidney transplantationstatic cold storage

Identifiers

PMID37685597
PMCPMC10488768

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.