Evidence map›Paper›PMID 37685556›Full record

ReviewJournal of clinical medicine2023

The Role of FDG-PET in the Evaluation of Hidradenitis Suppurativa: A Systematic Review.

Sahithi Talasila, Eric M Teichner, Robert C Subtirelu, David H Xiang, Cyrus Ayubcha, Thomas Werner, Abass Alavi, Mona-Elisabeth Revheim

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Sahithi TalasilaSidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Eric M TeichnerSidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.ORCID 0000-0001-6627-6550
Robert C SubtireluDepartment of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.
David H XiangHarvard Medical School, Harvard University, Boston, MA 02115, USA.
Cyrus AyubchaHarvard Medical School, Harvard University, Boston, MA 02115, USA.
Thomas WernerDepartment of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.
Abass AlaviDepartment of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-2442-7901
Mona-Elisabeth RevheimThe Intervention Centre, Division of Technology and Innovation, Oslo University Hospital, 0424 Oslo, Norway.ORCID 0000-0003-3300-7420
Hospital of the University of Pennsylvania · USHarvard University · USThomas Jefferson University · USOslo University Hospital · NO

Funding

Medical Scientist Training ProgramT32GM007753 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WALENSKY, LOREN DAVID · 1985 to 2021
$50.0M
Medical Scientist Training ProgramT32GM144273 · NIGMS · HARVARD MEDICAL SCHOOL · PI David Shumway Jones, Jacqueline A. Lees · 2022 to 2026
$14.7M
NIGMS NIH HHS T32 GM007753NIGMS NIH HHS T32 GM144273
6 · The paper itself

Abstract

Hidradenitis suppurativa (HS) is a chronic skin disorder characterized by nodules, comedones, and sinus tracts that often leave prominent scarring. In recent years, non-invasive imaging techniques have been used to assess the inflammatory activity, vascularization, and treatment response of lesions. Specifically, fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) scans may aid in identifying systemic inflammation in patients with HS, improving diagnosis. Inflamed hypermetabolic tissues exhibit a greater uptake of FDG due to increased glucose uptake and vascularity. A systematic review was conducted to summarize the utility of nuclear imaging techniques in the diagnosis and treatment follow-up of HS. PubMed, Scopus, and ScienceDirect databases were utilized for relevant articles discussing the utility of PET scans in managing HS. A total of 51 citations were identified in the initial search. Following the review of titles, abstracts, and duplicates, 43 articles were excluded, leaving a total of eight articles for analysis. Data were extracted from each article, encompassing the number of patients, imaging techniques employed, and final results. An analysis of the data demonstrated that FDG-PET showed evidence of identifying subclinical lesions of the disease, improving the visualization of HS, and providing an objective method of assessing severity.

Indexed as

diagnosisFDG-PET/CTfluorine-18 fluorodeoxyglucosehidradenitis suppurativanon-invasive imaging techniquesSAPHO syndromesystemic inflammationtreatment follow-up

Identifiers

PMID37685556
PMCPMC10488012
OpenAlexW4386134707

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.