Evidence map›Paper›PMID 37685555›Full record

ArticleJournal of clinical medicine2023

Intraoperative Blood Pressure and Carbon Dioxide Values during Aneurysmal Repair and the Outcomes after Aneurysmal Subarachnoid Hemorrhage.

Umeshkumar Athiraman, Aaron J Norris, Keshav Jayaraman, Abhijit V Lele, Rainer Kentner, Preet Mohinder Singh, Omokhaye M Higo, Gregory J Zipfel, Rajat Dhar

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Umeshkumar AthiramanDepartment of Anesthesiology, Washington University, St. Louis, MO 63110, USA.ORCID 0000-0002-9086-0607
Aaron J NorrisDepartment of Anesthesiology, Washington University, St. Louis, MO 63110, USA.
Keshav JayaramanDepartment of Anesthesiology, Washington University, St. Louis, MO 63110, USA.ORCID 0000-0002-5227-7023
Abhijit V LeleDepartment of Anesthesiology, University of Washington, Seattle, WA 98122, USA.ORCID 0000-0002-6956-538X
Rainer KentnerDepartment of Anesthesiology, Washington University, St. Louis, MO 63110, USA.
Preet Mohinder SinghDepartment of Anesthesiology, Washington University, St. Louis, MO 63110, USA.
Omokhaye M HigoDepartment of Anesthesiology, Washington University, St. Louis, MO 63110, USA.
Gregory J ZipfelDepartments of Neurological Surgery and Neurology, Washington University, St. Louis, MO 63110, USA.
Rajat DharDepartment of Neurology, Washington University, St. Louis, MO 63110, USA.
Washington University in St. Louis · USNeurological Surgery · USUniversity of Washington · US

Funding

Translating Endogenous Vascular Protective Cascades into Therapy for Aneurysmal Subarachnoid HemorrhageR01NS091603 · NINDS · WASHINGTON UNIVERSITY · PI ZIPFEL, GREGORY J · 2015 to 2019
$2.5M
Genetic Architecture of Cerebral Edema after StrokeR01NS121218 · NINDS · WASHINGTON UNIVERSITY · PI Rajat Raj Dhar · 2022 to 2026
$1.9M
Molecular mechanisms underlying isoflurane conditioning-induced neurovascular protection in subarachnoid hemorrhageK08NS125038 · NINDS · WASHINGTON UNIVERSITY · PI Umeshkumar Athiraman · 2022 to 2026
$891k
NINDS NIH HHS K08 NS125038NINDS NIH HHS R01 NS091603NINDS NIH HHS R01 NS121218
6 · The paper itself

Abstract

Cerebral autoregulation impairment is a critical aspect of subarachnoid hemorrhage (SAH)-induced secondary brain injury and is also shown to be an independent predictor of delayed cerebral ischemia (DCI) and poor neurologic outcomes. Interestingly, intraoperative hemodynamic and ventilatory parameters were shown to influence patient outcomes after SAH. The aim of the current study was to evaluate the association of intraoperative hypotension and hypocapnia with the occurrence of angiographic vasospasm, DCI, and neurologic outcomes at discharge. Intraoperative data were collected for 390 patients with aneurysmal SAH who underwent general anesthesia for aneurysm clipping or coiling between January 2010 and May 2018. We measured the mean intraoperative blood pressure and end-tidal carbon dioxide (ETCO

Indexed as

cerebral vasospasmdelayed cerebral ischemiaend-tidal carbon dioxideintraoperative blood pressureneurologic outcomessubarachnoid hemorrhage

Identifiers

PMID37685555
PMCPMC10488211
OpenAlexW4386121663

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.