ArticleJournal of clinical medicine2023
Agreement between Five Experts and the Laguna ONhE Automatic Colourimetric Application Interpreting the Glaucomatous Aspect of the Optic Nerve.
Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Combined diagnostic accuracy of two artificial intelligence systems for glaucoma diagnosis using color fundus photography.PloS one · 2026Article
- Correlation of optic nerve hemoglobin levels with structural and functional parameters in glaucoma.Scientific reports · 2025Article
- Estimation of normal and glaucomatous optic nerve morphology from perfusion.BMJ open ophthalmology · 2025Article
- Synergistic AI-resident approach achieves superior diagnostic accuracy in tertiary ophthalmic care for glaucoma and retinal disease.Frontiers in ophthalmology · 2025Article
- Identification of Glaucoma in Diabetics Using the Laguna-ONhE Colourimetric Method and OCT Spectralis.Journal of clinical medicine · 2023Article
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5 authors.
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Abstract
backgroundOptic nerve head (ONH) interpretation is a glaucoma screening method which may be influenced by criteria variability. Laguna ONhE software is a low-cost and non-invasive method of ONH analysis.
methodsWe analysed the results of the Laguna ONhE application, interpreting 552 ONH images from the ACRIMA database, publicly available on the Internet, and compared them with the opinion of five experts. Diagnostic agreement was investigated using Cohen's kappa (κ) with 95% confidence.
resultsThe kappa concordance index obtained with Laguna ONhE and the majority of the experts' criterion (0.77) was significantly higher compared to that obtained with ACRIMA and the majority of the experts' criterion (0.61). In 44.7% of the cases there was absolute agreement among the 5 experts and the Laguna ONhE program. Removing borderline cases from the analysis yielded increased diagnostic agreement (0.81). The area under the receiver operating characteristic (AUROC) of the Laguna ONhE program (0.953,
conclusionsLaguna ONhE's agreement with the experts is high, particularly where the diagnosis may be more obvious by the appearance of the ONH.
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