Evidence map›Paper›PMID 37685547›Full record

ArticleJournal of clinical medicine2023

A Machine Learning Model for the Accurate Prediction of 1-Year Survival in TAVI Patients: A Retrospective Observational Cohort Study.

Francesco Pollari, Wolfgang Hitzl, Magnus Rottmann, Ferdinand Vogt, Miroslaw Ledwon, Christian Langhammer, Dennis Eckner, Jürgen Jessl, Thomas Bertsch, Matthias Pauschinger and 1 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Francesco PollariCardiac Surgery, Cardiovascular Center, Paracelsus Medical University-Klinikum Nuremberg, 90471 Nuremberg, Germany.ORCID 0000-0003-1729-532X
Wolfgang HitzlResearch and Innovation Management (RIM), Team Biostatistics and Publication of Clinical Trial Studies, Paracelsus Medical University, 5020 Salzburg, Austria.ORCID 0000-0002-7696-1479
Magnus RottmannCardiac Surgery, Cardiovascular Center, Paracelsus Medical University-Klinikum Nuremberg, 90471 Nuremberg, Germany.
Ferdinand VogtCardiac Surgery, Cardiovascular Center, Paracelsus Medical University-Klinikum Nuremberg, 90471 Nuremberg, Germany.
Miroslaw LedwonCardiac Surgery, Cardiovascular Center, Paracelsus Medical University-Klinikum Nuremberg, 90471 Nuremberg, Germany.
Christian LanghammerInstitute of Clinical Chemistry, Laboratory Medicine and Transfusion Medicine, Paracelsus Medical University, 90471 Nuremberg, Germany.
Dennis EcknerCardiology, Cardiovascular Center, Paracelsus Medical University-Klinikum Nuremberg, 90419 Nuremberg, Germany.ORCID 0000-0003-4791-0098
Jürgen JesslCardiology, Cardiovascular Center, Paracelsus Medical University-Klinikum Nuremberg, 90419 Nuremberg, Germany.
Thomas BertschInstitute of Clinical Chemistry, Laboratory Medicine and Transfusion Medicine, Paracelsus Medical University, 90471 Nuremberg, Germany.
Matthias PauschingerCardiology, Cardiovascular Center, Paracelsus Medical University-Klinikum Nuremberg, 90419 Nuremberg, Germany.
Theodor FischleinCardiac Surgery, Cardiovascular Center, Paracelsus Medical University-Klinikum Nuremberg, 90471 Nuremberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundpredicting the 1-year survival of patients undergoing transcatheter aortic valve implantation (TAVI) is indispensable for managing safe early discharge strategies and resource optimization.

methodsRoutinely acquired data (134 variables) were used from 629 patients, who underwent transfemoral TAVI from 2012 up to 2018. Support vector machines, neuronal networks, random forests, nearest neighbour and Bayes models were used with new, previously unseen patients to predict 1-year mortality in TAVI patients. A genetic variable selection algorithm identified a set of predictor variables with high predictive power.

resultsUnivariate analyses revealed 19 variables (clinical, laboratory, echocardiographic, computed tomographic and ECG) that significantly influence 1-year survival. Before applying the reject option, the model performances in terms of negative predictive value (NPV) and positive predictive value (PPV) were similar between all models. After applying the reject option, the random forest model identified a subcohort showing a negative predictive value of 96% (positive predictive value = 92%, accuracy = 96%).

conclusionsOur model can predict the 1-year survival with very high negative and sufficiently high positive predictive value, with very high accuracy. The "reject option" allows a high performance and harmonic integration of machine learning in the clinical decision process.

Indexed as

machine learningoutcomepersonalizedpredictionsurvivalTAVI

Identifiers

PMID37685547
PMCPMC10488486

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.