Evidence map›Paper›PMID 37685526›Full record

ArticleJournal of clinical medicine2023

Prediction and Prevention of Preterm Birth: Secondary Analysis of a Randomized Intervention Trial.

C Andrew Combs, John A F Zupancic, Michael Walker, Jing Shi

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

C Andrew CombsPediatrix Center for Research, Education, Quality & Safety, Sunrise, FL 33323, USA.ORCID 0000-0002-5571-9579
John A F ZupancicDepartment of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
Michael WalkerStatistics Consultant, Carlsbad, CA 92009, USA.ORCID 0009-0004-2677-794X
Jing ShiStatistics Consultant, Carlsbad, CA 92009, USA.
Beth Israel Deaconess Medical Center · US

Funding

Sera Prognostics, Inc N/A
6 · The paper itself

Abstract

Our objective was to evaluate whether pregnancy is prolonged by the use of a proteomics-based maternal serum screening test followed by treatment interventions. This is a secondary analysis of the PREVENT-PTB randomized trial comparing screening with the PreTRM test versus no screening. The primary trial analysis found no significant between-group difference in the preterm birth rate. Rather than considering a dichotomous outcome (preterm versus term), we treated gestational age at birth as a continuous variable using survival analysis. We also evaluated between-group difference in NICU length of stay and duration of respiratory support. Results indicated that pregnancy was significantly prolonged in subjects screened with the PreTRM test compared to controls (adjusted hazard ratio 0.53, 95% confidence interval 0.36-0.78,

Indexed as

17-hydroxyprogesterone caproatecare managementlength of staylow-dose aspirinneonatal respiratory morbiditypreterm birthproteomic biomarkersrisk assessment

Identifiers

PMID37685526
PMCPMC10487576
OpenAlexW4386096340

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.