Evidence map›Paper›PMID 37685525›Full record

ArticleJournal of clinical medicine2023

Native Renal Arteries Denervation as a Therapy of Refractory Hypertension in Patient after Heart and Kidney Transplantation-5 Years of Observation.

Justyna Pilch, Jakub Mizera, Krzysztof Wiśnicki, Marcin Protasiewicz, Jacek Kurcz, Sławomir Zmonarski, Patryk Wawrzonkowski, Krzysztof Letachowicz, Dorota Kamińska, Tomasz Gołębiowski and 3 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 68% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Justyna PilchFaculty of Medicine, Wroclaw Medical University, 50-368 Wroclaw, Poland.ORCID 0000-0001-8351-9622
Jakub MizeraFaculty of Medicine, Wroclaw Medical University, 50-368 Wroclaw, Poland.ORCID 0000-0002-8112-9257
Krzysztof WiśnickiClinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0003-1073-5759
Marcin ProtasiewiczClinical Department of Cardiology, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0003-0253-0585
Jacek KurczClinical Department of Radiology, Wroclaw Medical University, 50-556 Wroclaw, Poland.
Sławomir ZmonarskiClinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0002-0764-4939
Patryk WawrzonkowskiClinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland.
Krzysztof LetachowiczClinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0002-2747-8851
Dorota KamińskaClinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0003-2400-9328
Tomasz GołębiowskiClinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0001-5477-2020
Michał ZakliczyńskiInstitute of Heart Diseases, University Hospital, 50-556 Wroclaw, Poland.
Magdalena KrajewskaClinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0002-2632-2409
Mirosław BanasikClinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0002-0588-1551
Wroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report describes a 59-year-old male patient after heart and kidney transplantation, subsequently diagnosed with refractory hypertension since implemented antihypertensive pharmacotherapy consisting of six agents did not provide a substantial therapeutic response. Elevated blood pressure and its impact on a hypertrophied transplanted heart and impaired renal graft function have led to a significant deterioration in the patient's cardiovascular risk profile. To address this issue, a native renal arteries denervation was performed. It resulted in a noteworthy decrease in both systolic and diastolic pressure values, thus manifesting a positive hypotensive effect. Furthermore, a sustainable reduction of left ventricular mass and stabilization in kidney graft function were noticed. The presented case provides evidence that renal denervation can be an efficacious complementary treatment method in individuals who received kidney and heart grafts as it leads to a decrease in cardiovascular risk.

Indexed as

heart transplantationinnovative treatmentkidney transplantationrefractory hypertensionrenal arteries denervation

Identifiers

PMID37685525
PMCPMC10487959
OpenAlexW4386098448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.