Evidence map›Paper›PMID 37685508›Full record

ArticleJournal of clinical medicine2023

Hemi-Ultrathin Descemet Stripping Automated Endothelial Keratoplasty (Hemi-UT-DSAEK) Using Pediatric Donor Corneas: A Case Series.

Pia Leon, Lorena Francescutti, Pietro Gentile, Federica Birattari, Diego Ponzin, Davide Camposampiero, Antonella Franch, Mohit Parekh

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Pia LeonDepartment of Ophthalmology, SS Giovanni e Paolo Hospital, 30122 Venice, Italy.
Lorena FrancescuttiDepartment of Ophthalmology, SS Giovanni e Paolo Hospital, 30122 Venice, Italy.
Pietro GentileDepartment of Ophthalmology, SS Giovanni e Paolo Hospital, 30122 Venice, Italy.ORCID 0000-0002-5485-5237
Federica BirattariInternational Center for Ocular Physiopathology, Fondazione Banca degli Occhi del Veneto Onlus, Zelarino, 30174 Venice, Italy.
Diego PonzinInternational Center for Ocular Physiopathology, Fondazione Banca degli Occhi del Veneto Onlus, Zelarino, 30174 Venice, Italy.
Davide CamposampieroInternational Center for Ocular Physiopathology, Fondazione Banca degli Occhi del Veneto Onlus, Zelarino, 30174 Venice, Italy.
Antonella FranchDepartment of Ophthalmology, SS Giovanni e Paolo Hospital, 30122 Venice, Italy.
Mohit ParekhSchepens Eye Research Institute, Mass Eye and Ear, Boston, MA 02114, USA.ORCID 0000-0002-5186-068X
Ospedale San Paolo · ITVeneto Eye Bank Foundation · ITMassachusetts Eye and Ear Infirmary · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe sought to evaluate the clinical outcomes of hemi-UT-DSAEK grafts from the pediatric donor corneas of patients affected by Fuchs Endothelial Corneal Dystrophy (FECD).

methodsA prospective, interventional case series was conducted at the Ophthalmology Department of Venice Civil Hospital and the Veneto Eye Bank Foundation (Venice, Italy). Six eyes of six patients affected by FECD received large-diameter, semicircular hemi-UT-DSAEK grafts obtained from three pediatric donor corneas using the standard pull-through method. Endothelial cell density (ECD), central corneal thickness (CCT), best-corrected visual acuity (BCVA) and intraoperative and postoperative complications were recorded at different time intervals up to 12 months.

resultsThe average donor age was 64.6 ± 8.6 years, and the pre-operative ECD was 3266 ± 225 cells/mm

conclusionsHemi-UT-DSAEK grafts using pediatric donor corneas are surgically feasible and can provide similar clinical outcomes compared to conventional UT-DSAEK. Transplanting pediatric donor tissues with high ECD into two patients could potentially increase the donor tissue pool to treat endothelial disease.

Indexed as

corneaendotheliumeye bankFECDhemi-UT-DSAEKpediatric donorsUT-DSAEK

Identifiers

PMID37685508
PMCPMC10487646
OpenAlexW4386070272

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.