Evidence map›Paper›PMID 37685480›Full record

ReviewHealthcare (Basel, Switzerland)2023

Effectiveness of Osteopathic Manipulative Treatment in Adults with Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis.

Francesca Buffone, Andrea Gianmaria Tarantino, Federico Belloni, Andrea Spadafora, Giorgio Bolzoni, Irene Bruini, Andrea Bergna, Luca Vismara

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Healthcare (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07176078 (Evaluating the Added Benefit of Osteopathic Care to a Flexi-FODMAP Diet in Fibromyalgia Patients With Irritable Bowel Syndrome), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07176078 narecruitingnot on this mapstarted 2026, after this paper: background citation

Evaluating the Added Benefit of Osteopathic Care to a Flexi-FODMAP Diet in Fibromyalgia Patients With Irritable Bowel Syndrome: a Randomized Sham-controlled Trial

TypeinterventionalSponsorUniversitair Ziekenhuis BrusselRan2026 to 2027Enrolled96ConditionsIrritable Bowel Syndrome (IBS), Fibromyalgia (FM)ArmsOsteopathic care, Sham Osteopathic care, Flexi-FODMAP Diet
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Francesca BuffoneDivision of Paediatric, Manima Non-Profit Organization Social Assistance and Healthcare, 20125 Milan, Italy.ORCID 0000-0002-9363-9190
Andrea Gianmaria TarantinoDivision of Paediatric, Manima Non-Profit Organization Social Assistance and Healthcare, 20125 Milan, Italy.ORCID 0000-0001-9911-6270
Federico BelloniResearch Department, SOMA Istituto Osteopatia Milano, 20126 Milan, Italy.
Andrea SpadaforaResearch Department, SOMA Istituto Osteopatia Milano, 20126 Milan, Italy.
Giorgio BolzoniResearch Department, SOMA Istituto Osteopatia Milano, 20126 Milan, Italy.
Irene BruiniDivision of Paediatric, Manima Non-Profit Organization Social Assistance and Healthcare, 20125 Milan, Italy.ORCID 0009-0000-6783-2539
Andrea BergnaResearch Department, SOMA Istituto Osteopatia Milano, 20126 Milan, Italy.ORCID 0000-0002-2526-9642
Luca VismaraDivision of Neurology and Neurorehabilitation, IRCCS Istituto Auxologico Italiano, 28824 Piancavallo-Verbania, Italy.ORCID 0000-0001-9034-7101
Harvard University · USIRCCS Istituto Auxologico Italiano · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this systematic review and meta-analysis was to evaluate the effectiveness of the osteopathic manipulative treatment (OMT) in adults with irritable bowel syndrome (IBS). A literature resview was carried out on the following databases: PubMed, Embase, Cochrane, Cinahl, Scopus, PEDro and ClinicalTrials.gov. 350 articles were recovered. Eligibility criteria were evaluated by two independent reviewers, including randomized controlled trials (RCTs), quasi-RCTs, or ongoing RCTs with OMT compared to any kind of control in patients diagnosed with IBS. Six studies (five RCTs and one ongoing RCT) were considered eligible. Four RCTs were classified as some concerns and one as high risk of bias. In the meta-analysis, OMT compared to sham/no intervention showed statistically significant results for abdominal pain (effect size ES = -1.14 [-1.66, -0.62];

Indexed as

adultsgastrointestinal symptomsirritable bowel syndromemanual therapyosteopathic manipulative treatment

Identifiers

PMID37685480
PMCPMC10487478
OpenAlexW4386324413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.