Evidence map›Paper›PMID 37685380›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Quantitative Chest X-ray Radiomics for Therapy Response Monitoring in Patients with Pulmonary Tuberculosis.

Tamarisk Du Plessis, William Ian Duncombe Rae, Gopika Ramkilawon, Neil Alexander Martinson, Mike Michael Sathekge

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tamarisk Du PlessisDepartment of Nuclear Medicine, Faculty of Health Sciences, University of Pretoria, Pretoria 0001, South Africa.ORCID 0000-0002-3955-1833
William Ian Duncombe RaeMedical Imaging Department, Prince of Wales Hospital, Sydney, NSW 2031, Australia.
Gopika RamkilawonDepartment of Statistics, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria 0081, South Africa.ORCID 0000-0002-2919-1918
Neil Alexander MartinsonPerinatal HIV Research Unit (PHRU), University of the Witwatersrand, Johannesburg 1862, South Africa.
Mike Michael SathekgeDepartment of Nuclear Medicine, Faculty of Health Sciences, University of Pretoria, Pretoria 0001, South Africa.ORCID 0000-0002-2806-0625

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) remains the second leading cause of death globally from a single infectious agent, and there is a critical need to develop improved imaging biomarkers and aid rapid assessments of responses to therapy. We aimed to utilize radiomics, a rapidly developing image analysis tool, to develop a scoring system for this purpose. A chest X-ray radiomics score (RadScore) was developed by implementing a unique segmentation method, followed by feature extraction and parameter map construction. Signature parameter maps that showed a high correlation to lung pathology were consolidated into four frequency bins to obtain the RadScore. A clinical score (TBscore) and a radiological score (RLscore) were also developed based on existing scoring algorithms. The correlation between the change in the three scores, calculated from serial X-rays taken while patients received TB therapy, was evaluated using Spearman's correlation. Poor correlations were observed between the changes in the TBscore and the RLscore (0.09 (

Indexed as

chest X-raysfeature extractionradiomicsradiomics scoresegmentationtuberculosis

Identifiers

PMID37685380
PMCPMC10486768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.