Evidence map›Paper›PMID 37685368›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Correlation between Chest Computed Tomography Score and Laboratory Biomarkers in the Risk Stratification of COVID-19 Patients Admitted to the Emergency Department.

Cartesio D'Agostini, Jacopo M Legramante, Marilena Minieri, Vito N Di Lecce, Maria Stella Lia, Massimo Maurici, Ilaria Simonelli, Marco Ciotti, Carla Paganelli, Alessandro Terrinoni and 8 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Cartesio D'AgostiniDepartment of Experimental Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
Jacopo M LegramanteDepartment of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
Marilena MinieriDepartment of Experimental Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-2512-4793
Vito N Di LecceEmergency Department, Tor Vergata University Hospital, 00133 Rome, Italy.
Maria Stella LiaUnit of Laboratory Medicine, Tor Vergata University Hospital, 00133 Rome, Italy.
Massimo MauriciDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0001-5884-161X
Ilaria SimonelliNursing Science and Public Health, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-6172-1317
Marco CiottiUnit of Virology, Tor Vergata University Hospital, 00133 Rome, Italy.ORCID 0000-0002-9943-9130
Carla PaganelliEmergency Department, Tor Vergata University Hospital, 00133 Rome, Italy.
Alessandro TerrinoniDepartment of Experimental Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-7442-2252
Alfredo GiovannelliUnit of Laboratory Medicine, Tor Vergata University Hospital, 00133 Rome, Italy.
Massimo PieriDepartment of Experimental Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-3463-0268
Mariacarla GallùDepartment of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
Vito Dell'OlioDepartment of Surgical Science, University of Rome Tor Vergata, 00133 Rome, Italy.
Carla PreziosoLaboratory of Microbiology of Chronic-Neurodegenerative Diseases, IRCCS San Raffaele Roma, 00166 Rome, Italy.
Dolores LimongiDepartment of Human Sciences and Quality of Life Promotion, San Raffaele University, 00166 Rome, Italy.
Sergio BernardiniDepartment of Experimental Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
Antonio OrlacchioDepartment of Surgical Science, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-7053-8813
University of Rome Tor Vergata · ITSan Raffaele University of Rome · ITVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt has been reported that mid-regional proadrenomedullin (MR-proADM) could be considered a useful tool to stratify the mortality risk in COVID-19 patients upon admission to the emergency department (ED). During the COVID-19 outbreak, computed tomography (CT) scans were widely used for their excellent sensitivity in diagnosing pneumonia associated with SARS-CoV-2 infection. However, the possible role of CT score in the risk stratification of COVID-19 patients upon admission to the ED is still unclear.

aimThe main objective of this study was to assess if the association of the CT findings alone or together with MR-proADM results could ameliorate the prediction of in-hospital mortality of COVID-19 patients at the triage. Moreover, the hypothesis that CT score and MR-proADM levels together could play a key role in predicting the correct clinical setting for these patients was also evaluated.

methodsEpidemiological, demographic, clinical, laboratory, and outcome data were assessed and analyzed from 265 consecutive patients admitted to the triage of the ED with a SARS-CoV-2 infection. RESULTS AND

conclusionsThe accuracy results by AUROC analysis and statistical analysis demonstrated that CT score is particularly effective, when utilized together with the MR-proADM level, in the risk stratification of COVID-19 patients admitted to the ED, thus helping the decision-making process of emergency physicians and optimizing the hospital resources.

Indexed as

CT scoreemergency departmentlaboratory biomarkersMR-proadrenomedullin

Identifiers

PMID37685368
PMCPMC10486389
OpenAlexW4386380459

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.