Evidence map›Paper›PMID 37685352›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Integrating Artificial Intelligence Tools in the Clinical Research Setting: The Ovarian Cancer Use Case.

Lorena Escudero Sanchez, Thomas Buddenkotte, Mohammad Al Sa'd, Cathal McCague, James Darcy, Leonardo Rundo, Alex Samoshkin, Martin J Graves, Victoria Hollamby, Paul Browne and 6 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Lorena Escudero SanchezDepartment of Radiology, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0003-3464-9206
Thomas BuddenkotteDepartment of Radiology, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0003-4872-4246
Mohammad Al Sa'dNational Cancer Imaging Translational Accelerator (NCITA) Consortium, UK.
Cathal McCagueDepartment of Radiology, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0002-9588-267X
James DarcyNational Cancer Imaging Translational Accelerator (NCITA) Consortium, UK.
Leonardo RundoDepartment of Radiology, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0003-3341-5483
Alex SamoshkinOffice for Translational Research, School of Clinical Medicine, University of Cambridge, Cambridge CB2 0SP, UK.ORCID 0000-0001-6296-2254
Martin J GravesDepartment of Radiology, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0003-4327-3052
Victoria HollambyResearch and Information Governance, School of Clinical Medicine, University of Cambridge, Cambridge CB2 0SP, UK.ORCID 0009-0002-5807-446X
Paul BrowneHigh Performance Computing Department, University of Cambridge, Cambridge CB3 0RB, UK.
Mireia Crispin-OrtuzarCancer Research UK Cambridge Centre, Li Ka Shing Centre, Cambridge CB2 0RE, UK.
Ramona WoitekDepartment of Radiology, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0002-9146-9159
Evis SalaDepartment of Radiology, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0002-5518-9360
Carola-Bibiane SchönliebDepartment of Applied Mathematics and Theoretical Physics, University of Cambridge, Wilberforce Road, Cambridge CB3 0WA, UK.
Simon J DoranNational Cancer Imaging Translational Accelerator (NCITA) Consortium, UK.ORCID 0000-0001-8569-9188
Ozan ÖktemDepartment of Mathematics, KTH-Royal Institute of Technology, SE-100 44 Stockholm, Sweden.

Funding

Cancer Research UK C42780/A27066Wellcome TrustWellcome Trust 215733/Z/19/Z
6 · The paper itself

Abstract

Artificial intelligence (AI) methods applied to healthcare problems have shown enormous potential to alleviate the burden of health services worldwide and to improve the accuracy and reproducibility of predictions. In particular, developments in computer vision are creating a paradigm shift in the analysis of radiological images, where AI tools are already capable of automatically detecting and precisely delineating tumours. However, such tools are generally developed in technical departments that continue to be siloed from where the real benefit would be achieved with their usage. Significant effort still needs to be made to make these advancements available, first in academic clinical research and ultimately in the clinical setting. In this paper, we demonstrate a prototype pipeline based entirely on open-source software and free of cost to bridge this gap, simplifying the integration of tools and models developed within the AI community into the clinical research setting, ensuring an accessible platform with visualisation applications that allow end-users such as radiologists to view and interact with the outcome of these AI tools.

Indexed as

artificial intelligencecancer researchclinical integrationimagingradiomics

Identifiers

PMID37685352
PMCPMC10486639

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.