Evidence map›Paper›PMID 37685264›Full record

ReviewDiagnostics (Basel, Switzerland)2023

How Much Is Enough? A Surgical Perspective on Imaging Modalities to Estimate Function and Volume of the Future Liver Remnant before Hepatic Resection.

Flavio Milana, Simone Famularo, Michele Diana, Kohei Mishima, Elisa Reitano, Hwui-Dong Cho, Ki-Hun Kim, Jacques Marescaux, Matteo Donadon, Guido Torzilli

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Liver Resection for Hepatocellular Carcinoma: Recent Advances.Journal of clinical and experimental hepatology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Flavio MilanaDepartment of Biomedical Sciences, Humanitas University, Via Montalcini 4, 20090 Pieve Emanuele, MI, Italy.ORCID 0000-0003-3570-9573
Simone FamularoDepartment of Biomedical Sciences, Humanitas University, Via Montalcini 4, 20090 Pieve Emanuele, MI, Italy.ORCID 0000-0002-9721-6304
Michele DianaResearch Institute Against Digestive Cancer (IRCAD), 67000 Strasbourg, France.ORCID 0000-0002-1390-8486
Kohei MishimaResearch Institute Against Digestive Cancer (IRCAD), 67000 Strasbourg, France.ORCID 0000-0003-4284-2989
Elisa ReitanoResearch Institute Against Digestive Cancer (IRCAD), 67000 Strasbourg, France.ORCID 0000-0002-4286-8866
Hwui-Dong ChoDivision of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea.
Ki-Hun KimDivision of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea.
Jacques MarescauxResearch Institute Against Digestive Cancer (IRCAD), 67000 Strasbourg, France.ORCID 0000-0002-1400-6230
Matteo DonadonDepartment of Health Sciences, Università del Piemonte Orientale, 28100 Novara, NO, Italy.ORCID 0000-0003-0296-7648
Guido TorzilliDepartment of Biomedical Sciences, Humanitas University, Via Montalcini 4, 20090 Pieve Emanuele, MI, Italy.ORCID 0000-0001-5798-5021
Institut de Recherche contre les Cancers de l’Appareil Digestif · FRUlsan College · KRHumanitas University · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver resection is the first curative option for most hepatic primary and secondary malignancies. However, post-hepatectomy liver failure (PHLF) still represents a non-negligible postoperative complication, embodying the most frequent cause of hepatic-related mortality. In the absence of a specific treatment, the most effective way to deal with PHLF is its prevention through a careful preoperative assessment of future liver remnant (FLR) volume and function. Apart from the clinical score and classical criteria to define the safe limit of resectability, new imaging modalities have shown their ability to assist surgeons in planning the best operative strategy with a precise estimation of the FLR amount. New technologies leading to liver and tumor 3D reconstruction may guide the surgeon along the best resection planes combining the least liver parenchymal sacrifice with oncological appropriateness. Integration with imaging modalities, such as hepatobiliary scintigraphy, capable of estimating total and regional liver function, may bring about a decrease in postoperative complications. Magnetic resonance imaging with hepatobiliary contrast seems to be predominant since it simultaneously integrates hepatic function and volume information along with a precise characterization of the target malignancy.

Indexed as

image-guided surgeryliver resectionliver surgerypost-hepatectomy liver failureprecision surgery

Identifiers

PMID37685264
PMCPMC10486462
OpenAlexW4386067779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.