Evidence map›Paper›PMID 37685004›Full record

ArticleAnimals : an open access journal from MDPI2023

Reduced Nitric Oxide Synthase Involvement in Aigamo Duck Basilar Arterial Relaxation.

Siyuan Wu, Tomoki Ootawa, Ryoya Sekio, Henry Smith, Md Zahorul Islam, Ha Thi Thanh Nguyen, Yasuhiro Uno, Mitsuya Shiraishi, Atsushi Miyamoto

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Siyuan WuDepartment of Basic Veterinary Science, Joint Graduate School of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan.ORCID 0000-0002-5950-3433
Tomoki OotawaDepartment of Basic Veterinary Science, Joint Graduate School of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan.ORCID 0009-0000-1243-0698
Ryoya SekioDepartment of Veterinary Pharmacology, Joint Faculty of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan.
Henry SmithDepartment of Basic Veterinary Science, Joint Graduate School of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan.
Md Zahorul IslamDepartment of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.ORCID 0000-0003-4253-6711
Ha Thi Thanh NguyenDepartment of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine, Vietnam National University of Agriculture, Gia Lam, Hanoi 131000, Vietnam.ORCID 0000-0003-2059-7492
Yasuhiro UnoDepartment of Basic Veterinary Science, Joint Graduate School of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan.
Mitsuya ShiraishiDepartment of Basic Veterinary Science, Joint Graduate School of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan.ORCID 0000-0001-7737-0075
Atsushi MiyamotoDepartment of Basic Veterinary Science, Joint Graduate School of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan.ORCID 0000-0002-1980-2869
Kagoshima University · JPBangladesh Agricultural University · BDVietnam National University of Agriculture · VN

Funding

JPSP KAKENHI 16580242Vietnam National Foundation for Science and Technology Development 09/2019/ TN
6 · The paper itself

Abstract

The basilar arterial endothelium mediates blood vessel relaxation partly through the release of nitric oxide (NO). Apoptosis of cerebrovascular endothelial cells is linked to a high mortality rate in chickens infected with the highly pathogenic avian influenza virus, but interestingly, ducks exhibit a greater resistance to this virus. In this study, we examined the responsiveness of duck basilar arteries (BAs) to various vasoactive substances, including 5-hydroxytryptamine (5-HT), histamine (His), angiotensin (Ang) II, noradrenaline (NA), acetylcholine (ACh), and avian bradykinin ornithokinin (OK), aiming to characterize the receptor subtypes involved and the role of endothelial NO in vitro. Our findings suggest that arterial contraction is mediated with 5-HT

Indexed as

cerebral arteryduckendotheliumhighly pathogenic avian influenzanitric oxide

Identifiers

PMID37685004
PMCPMC10486467
OpenAlexW4386255931

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.