Evidence map›Paper›PMID 37684493›Full record

ArticleAdvances in therapy2023

Greenhouse Gas Emissions from Respiratory Treatments: Results from the SABA CARBON International Study.

Ashraf Alzaabi, John P Bell, Felicia Montero-Arias, David B Price, David J Jackson, Hao-Chien Wang, Nigel Budgen, Hisham Farouk, Ekaterina Maslova

Open access · hybridAbstract read
In one paragraph

Article in Advances in therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Environmental sustainability in asthma: reducing carbon footprint and medication wastage.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Contributions of Medical Greenhouse Gases to Climate Change and Their Possible Alternatives.International journal of environmental research and public health · 2024
    Review
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 5 countries.

Ashraf AlzaabiRespiratory Medicine Division, Zayed Military Hospital, Abu Dhabi, United Arab Emirates. ashrafalzaabi@uaeu.ac.ae.ORCID http://orcid.org/0000-0001-9840-2339
John P BellBioPharmaceutical Medical, Medical Affairs Respiratory and Immunology, AstraZeneca, Baar, Switzerland.ORCID http://orcid.org/0000-0001-9307-1235
Felicia Montero-AriasServicio de Neumología, Hospital México, CCSS y Hospital Clínica Bíblica Santa Ana, San José, Costa Rica.ORCID http://orcid.org/0000-0003-2909-6619
David B PriceObservational and Pragmatic Research Institute, Singapore, Singapore.ORCID http://orcid.org/0000-0002-9728-9992
David J JacksonGuy's Severe Asthma Centre, King's College London, London, UK.ORCID http://orcid.org/0000-0002-2299-868X
Hao-Chien WangDepartment of Medicine, National Taiwan University Cancer Center, Taipei City, Taiwan.ORCID http://orcid.org/0000-0002-7528-7494
Nigel BudgenGlobal Sustainability, AstraZeneca, Macclesfield, UK.ORCID http://orcid.org/0000-0001-8857-804X
Hisham FaroukInternational Medical, AstraZeneca, Dubai, United Arab Emirates.ORCID http://orcid.org/0000-0001-9445-3307
Ekaterina MaslovaBioPharmaceutical Medical, Medical Affairs Respiratory and Immunology, AstraZeneca, Cambridge, UK.ORCID http://orcid.org/0000-0001-5415-8119
AstraZeneca (United Kingdom) · GBAstraZeneca (Switzerland) · CHKing's College London · GBNational Taiwan University · TWUniversity of Aberdeen · GBZayed Military Hospital · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHealthcare systems are looking to reduce their carbon impact. Short-acting β

methodsTwo data sources were utilised to evaluate the carbon contribution of inhalers to respiratory care. To quantify greenhouse gas (GHG) emissions associated with total inhaler use across all respiratory indications, inhaler sales data were obtained from IQVIA MIDAS

resultsSABA accounted for > 50% of total inhaler use and inhaler-related emissions in most countries analysed. The total SABA-related emissions were estimated at 2.7 million tonnes carbon dioxide equivalents, accounting for 70% of total inhaler-related emissions. Among the countries, regions and economies analysed, per capita SABA use and associated emissions were higher in Australia, the Middle East and high-income countries. Most SABA prescriptions for asthma (> 90%) were given to patients already overusing SABA.

conclusionsGlobally, SABA use/overuse is widespread and is the greatest contributor to the carbon footprint of respiratory treatment, regardless of the economic status of countries. Implementing evidence-based treatment recommendations, personalising treatment and reducing healthcare inequities, especially in LMICs, may improve disease control and patient outcomes, thereby reducing SABA overuse and associated carbon emissions beyond SABA use alone.

Indexed as

AsthmaGreenhouse GasesAdministration, InhalationHumansNebulizers and VaporizersRetrospective StudiesGreenhouse GasesAsthmaAsthma controlCarbon footprintEnvironmental monitoringGreenhouse gas emissionsInhalersInhaler therapiesSABAShort-acting β2-agonist

Identifiers

PMID37684493
PMCPMC10567885
OpenAlexW4386564577

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.