Evidence map›Paper›PMID 37684380›Full record

ArticleScientific reports2023

Analysis of clinical features and identification of risk factors in patients with non-alcoholic fatty liver disease based on FibroTouch.

Yan Liao, Lei Liu, Jiayao Yang, Xiaoli Zhou, Xiaoli Teng, Yixi Li, Ying Wan, Jian Yang, Zhaohong Shi

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Observational
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yan LiaoDepartment of Gastroenterology, Wuhan No.1 Hospital, Wuhan, China. rm002136@whu.edu.cn.
Lei LiuDepartment of Pancreatic Surgery, Renmin Hospital of Wuhan University, Wuhan, China.
Jiayao YangDepartment of Gastroenterology, Wuhan No.1 Hospital, Wuhan, China.
Xiaoli ZhouDepartment of Gastroenterology, Wuhan No.1 Hospital, Wuhan, China.
Xiaoli TengDepartment of Gastroenterology, Wuhan No.1 Hospital, Wuhan, China.
Yixi LiDepartment of Gastroenterology, Wuhan No.1 Hospital, Wuhan, China.
Ying WanDepartment of Gastroenterology, Wuhan No.1 Hospital, Wuhan, China.
Jian YangDepartment of Gastroenterology, Wuhan No.1 Hospital, Wuhan, China.
Zhaohong ShiDepartment of Gastroenterology, Wuhan No.1 Hospital, Wuhan, China.
Wuhan No.1 Hospital · CNRenmin Hospital of Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our aim was to explore the correlation between ultrasound attenuation parameter (UAP) and liver stiffness measurement (LSM) based on FibroTouch (China) and clinical features in patients with non-alcoholic fatty liver disease (NAFLD), so as to provide a certain basis for the clinical application of FibroTouch in NAFLD. Hepatic steatosis and fibrosis in patients with NAFLD were graded according to FibroTouch, and the relationship between steatosis and fibrosis levels and clinical characteristics was retrospectively analyzed. Hepatic steatosis was positively related with weight, BMI, waist, hyperlipidemia, hyperuricemia, FBG, UA, TG, ALT, AST, GGT, LSM and hepatic fibrosis grading, and was negatively related with gender (male), age and AST/ALT ratio. Hepatic fibrosis was positively related with age, BMI, waist, hypertension, FBG, ALT, AST, GGT, NFS, APRI, FIB-4, UAP and hepatic steatosis grading, and was negatively related with blood platelet (PLT) counts. Moreover, BMI, waist, TG, ALT and LSM were independent risk factors of hepatic steatosis, while decreased PLT counts, AST and UAP were independent risk factors of hepatic fibrosis. Body mass parameters, metabolic risk factors and liver function indicators increase the risk of hepatic steatosis and fibrosis in patients with NAFLD, and UAP and LSM can interact with each other.

Indexed as

Non-alcoholic Fatty Liver DiseaseHumansLiver CirrhosisMalePatientsRetrospective StudiesRisk Factors

Identifiers

PMID37684380
PMCPMC10491815
OpenAlexW4386562747

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.