Evidence map›Paper›PMID 37684322›Full record

ArticleMolecular psychiatry2023

Incidence, prevalence, and global burden of ADHD from 1990 to 2019 across 204 countries: data, with critical re-analysis, from the Global Burden of Disease study.

Samuele Cortese, Minjin Song, Luis C Farhat, Dong Keon Yon, Seung Won Lee, Min Seo Kim, Seoyeon Park, Jae Won Oh, San Lee, Keun-Ah Cheon and 12 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Samuele Cortese *Centre for Innovation in Mental Health, School of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK. samuele.cortese@soton.ac.uk.
Minjin Song *Yonsei University College of Medicine, Seoul, South Korea.
Luis C Farhat *Universidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID 0000-0002-3147-8344
Dong Keon Yon *Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.ORCID 0000-0003-1628-9948
Seung Won Lee *Department of Precision Medicine, Sungkyunkwan University School of Medicine, Suwon, South Korea.ORCID 0000-0001-5632-5208
Min Seo KimDepartment of digital health, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, Samsung Medical Center, Seoul, Republic of Korea.
Seoyeon ParkYonsei University College of Medicine, Seoul, South Korea.
Jae Won OhDepartment of Psychiatry, Yongin Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-5379-9907
San LeeDepartment of Psychiatry, Yongin Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Keun-Ah CheonDivision of Child and Adolescent Psychiatry, Department of Psychiatry, Severance Hospital, Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0001-7113-9286
Lee SmithCentre for Health, Performance, and Wellbeing, Anglia Ruskin University, Cambridge, UK.
Corentin J GoslingCentre for Innovation in Mental Health, School of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.
Guilherme V PolanczykUniversidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID 0000-0003-2311-3289
Henrik LarssonSchool of Medical Sciences, Örebro University, Faculty of Medicine and Health, Örebro, Sweden.ORCID 0000-0002-6851-3297
Luis A RohdeADHD Outpatient Program & Developmental Psychiatry Program, Hospital de Clinica de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.ORCID 0000-0002-4552-4188
Stephen V FaraoneDepartment of Psychiatry and of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA.
Ai KoyanagiResearch and Development Unit, Parc Sanitari Sant Joan de Déu, CIBERSAM, ISCIII, Barcelona, Spain.
Elena DragiotiPain and Rehabilitation Centre, and Department of Medical and Health Sciences, Linköping University, Linköping, Sweden.ORCID 0000-0001-9019-4125
Joaquim RaduaInstitut d'Investigacions Biomediques August Pi i Sunyer, CIBERSAM, Instituto de Salud Carlos III, University of Barcelona, Barcelona, Spain.
Andre F CarvalhoIMPACT (Innovation in Mental and Physical Health and Clinical Treatment) Strategic Research Centre, School of Medicine, Barwon Health, Deakin University, Geelong, Australia.ORCID 0000-0002-2500-5671
Jae Il ShinDepartment of Pediatrics, Yonsei University College of Medicine, Seoul, Republic of Korea. shinji@yuhs.ac.ORCID 0000-0003-2326-1820
Marco SolmiCentre for Innovation in Mental Health, School of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.ORCID 0000-0003-4877-7233

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data on incidence, prevalence and burden of ADHD are crucial for clinicians, patients, and stakeholders. We present the incidence, prevalence, and burden of ADHD globally and across countries from 1990 to 2019 from the Global Burden of Disease (GBD) study. We also: (1) calculated the ADHD prevalence based on data actually collected as opposed to the prevalence estimated by the GBD with data imputation for countries without prevalence data; (2) discussed the GBD estimated ADHD burden in the light of recent meta-analytic evidence on ADHD-related mortality. In 2019, GBD estimated global age-standardized incidence and prevalence of ADHD across the lifespan at 0.061% (95%UI = 0.040-0.087) and 1.13% (95%UI = 0.831-1.494), respectively. ADHD accounted for 0.8% of the global mental disorder DALYs, with mortality set at zero by the GBD. From 1990 to 2019 there was a decrease of -8.75% in the global age-standardized prevalence and of -4.77% in the global age-standardized incidence. The largest increase in incidence, prevalence, and burden from 1990 to 2019 was observed in the USA; the largest decrease occurred in Finland. Incidence, prevalence, and DALYs remained approximately 2.5 times higher in males than females from 1990 to 2019. Incidence peaked at age 5-9 years, and prevalence and DALYs at age 10-14 years. Our re-analysis of data prior to 2013 showed a prevalence in children/adolescents two-fold higher (5.41%, 95% CI: 4.67-6.15%) compared to the corresponding GBD estimated prevalence (2.68%, 1.83-3.72%), with no significant differences between low- and middle- and high-income countries. We also found meta-analytic evidence of significantly increased ADHD-related mortality due to unnatural causes. While it provides the most detailed evidence on temporal trends, as well as on geographic and sex variations in incidence, prevalence, and burden of ADHD, the GBD may have underestimated the ADHD prevalence and burden. Given the influence of the GBD on research and policies, methodological issues should be addressed in its future editions.

Indexed as

Attention Deficit Disorder with HyperactivityGlobal Burden of DiseaseAdolescentChildChild, PreschoolFemaleGlobal HealthHumansIncidenceMalePrevalenceQuality-Adjusted Life Years

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.