Evidence map›Paper›PMID 37682823›Full record

ArticlePloS one2023

The impact of the early COVID-19 pandemic on healthcare system resource use and costs in two provinces in Canada: An interrupted time series analysis.

Seraphine Zeitouny, Douglas C Cheung, Karen E Bremner, Reka E Pataky, Priscila Pequeno, John Matelski, Stuart Peacock, M Elisabeth Del Giudice, Lauren Lapointe-Shaw, George Tomlinson and 9 more

Abstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
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  6. Oral corticosteroid overexposure: characterizing oral corticosteroid use in patients with chronic rhinosinusitis with nasal polypS in Canada (ACTIONS) results.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2025
    Article
  7. Article
  8. Trends in prescription opioid use for pain in Canada: a population-based repeated cross-sectional study of 6 provinces.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Article
  9. Article
  10. Review
  11. Observational
  12. Article
  13. Article
  14. Reducing Hospitalisations With a Skin and Soft Tissue Infection Clinic.Journal of evaluation in clinical practice · 2025
    Article
  15. Article
  16. Increased Severity of Multidrug-Resistant Shigella sonnei Infections in People Experiencing Homelessness.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Seraphine ZeitounyCanadian Centre for Applied Research in Cancer Control, BC Cancer, Vancouver, British Columbia, Canada.ORCID 0000-0003-2544-767X
Douglas C CheungToronto Health Economics and Technology Assessment (THETA) Collaborative, University Health Network, Toronto, Ontario, Canada.ORCID 0000-0002-9985-2443
Karen E BremnerToronto Health Economics and Technology Assessment (THETA) Collaborative, University Health Network, Toronto, Ontario, Canada.ORCID 0000-0003-4746-5828
Reka E PatakyCanadian Centre for Applied Research in Cancer Control, BC Cancer, Vancouver, British Columbia, Canada.
Priscila PequenoICES, Toronto, Ontario, Canada.
John MatelskiBiostatistics Research Unit, University Health Network, Toronto, Ontario, Canada.
Stuart PeacockCanadian Centre for Applied Research in Cancer Control, BC Cancer, Vancouver, British Columbia, Canada.
M Elisabeth Del GiudiceSunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Lauren Lapointe-ShawICES, Toronto, Ontario, Canada.
George TomlinsonBiostatistics Research Unit, University Health Network, Toronto, Ontario, Canada.
Andrew B MendlowitzToronto Health Economics and Technology Assessment (THETA) Collaborative, University Health Network, Toronto, Ontario, Canada.ORCID 0000-0002-0178-5087
Carol MulderChiefs of Ontario, Toronto, Ontario, Canada.
Teresa C O TsuiICES, Toronto, Ontario, Canada.ORCID 0000-0002-9806-9393
Nathan PerlisDivisions of Urology and Surgical Oncology, Department of Surgery, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Jennifer D WalkerICES, Toronto, Ontario, Canada.
Beate SanderToronto Health Economics and Technology Assessment (THETA) Collaborative, University Health Network, Toronto, Ontario, Canada.
William W L WongICES, Toronto, Ontario, Canada.
Murray D KrahnToronto Health Economics and Technology Assessment (THETA) Collaborative, University Health Network, Toronto, Ontario, Canada.
Girish S KulkarniDivisions of Urology and Surgical Oncology, Department of Surgery, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

Funding

CIHR NPC-178912CIHR VR4 172774
6 · The paper itself

Abstract

introductionThe aim of our study was to assess the initial impact of COVID-19 on total publicly-funded direct healthcare costs and health services use in two Canadian provinces, Ontario and British Columbia (BC).

methodsThis retrospective repeated cross-sectional study used population-based administrative datasets, linked within each province, from January 1, 2018 to December 27, 2020. Interrupted time series analysis was used to estimate changes in the level and trends of weekly resource use and costs, with March 16-22, 2020 as the first pandemic week. Also, in each week of 2020, we identified cases with their first positive SARS-CoV-2 test and estimated their healthcare costs until death or December 27, 2020.

resultsThe resources with the largest level declines (95% confidence interval) in use in the first pandemic week compared to the previous week were physician services [Ontario: -43% (-49%,-37%); BC: -24% (-30%,-19%) (both p<0.001)] and emergency department visits [Ontario: -41% (-47%,-35%); BC: -29% (-35%,-23%) (both p<0.001)]. Hospital admissions declined by 27% (-32%,-23%) in Ontario and 21% (-26%,-16%) in BC (both p<0.001). Resource use subsequently rose but did not return to pre-pandemic levels. Only home care and dialysis clinic visits did not significantly decrease compared to pre-pandemic. Costs for COVID-19 cases represented 1.3% and 0.7% of total direct healthcare costs in 2020 in Ontario and BC, respectively.

conclusionsReduced utilization of healthcare services in the overall population outweighed utilization by COVID-19 patients in 2020. Meeting the needs of all patients across all services is essential to maintain resilient healthcare systems.

Indexed as

COVID-19PandemicsBritish ColumbiaCross-Sectional StudiesHealth Care CostsHumansInterrupted Time Series AnalysisRenal DialysisRetrospective StudiesSARS-CoV-2

Identifiers

PMID37682823
PMCPMC10490868

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.