Evidence map›Paper›PMID 37682489›Full record

ArticleAging clinical and experimental research2023

Does age impact outcomes of retrograde intrarenal surgery in the elderly? Results from 366 patients from the FLEXible ureteroscopy outcomes registry (FLEXOR).

Carlo Giulioni, Carlo Brocca, Vineet Gauhar, Bhaskar Kumar Somani, Ben Hall Chew, Olivier Traxer, Esteban Emiliani, Takaki Innoue, Kemal Sarica, Nariman Gadzhiev and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Aging clinical and experimental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 8 countries.

Carlo GiulioniUrology Unit, Azienda Ospedaliero-Universitaria Delle Marche, Università Politecnica Delle Marche, Via Conca 71, 60126, Ancona, Italy. carlo.giulioni9@gmail.com.ORCID http://orcid.org/0000-0001-9934-4011
Carlo BroccaUrology Unit, Azienda Ospedaliero-Universitaria Delle Marche, Università Politecnica Delle Marche, Via Conca 71, 60126, Ancona, Italy.
Vineet GauharDepartment of Urology, Ng Teng Fong General Hospital, Jurong East, Singapore.
Bhaskar Kumar SomaniDepartment of Urology, University Hospitals Southampton, NHS Trust, Southampton, UK.
Ben Hall ChewDepartment of Urology, University of British Columbia, Vancouver, Canada.
Olivier TraxerDepartment of Urology AP-HP, Sorbonne University, Tenon Hospital, Paris, France.
Esteban EmilianiDepartment of Urology, Fundación Puigvert, Universidad Autónoma de Barcelona, Barcelona, Spain.
Takaki InnoueDepartment of Urology and Stone Center, Hara Genitourinary Hospital, Kobe, Hyogo, Japan.
Kemal SaricaDepartment of Urology, Biruni University Medical School, Istanbul, Turkey.
Nariman GadzhievEndourology department, Saint-Petersburg State Medical University, Saint-Petersburg, Russia.
Yiloren TanidirDepartment of Urology, Marmara University School of Medicine, Istanbul, Turkey.
Jeremy Yuen-Chun TeohDepartment of Surgery, Faculty of Medicine, S.H. Ho Urology Centre, The Chinese University of Hong Kong, Hong Kong, China.
Andrea Benedetto GalosiUrology Unit, Azienda Ospedaliero-Universitaria Delle Marche, Università Politecnica Delle Marche, Via Conca 71, 60126, Ancona, Italy.
Daniele CastellaniUrology Unit, Azienda Ospedaliero-Universitaria Delle Marche, Università Politecnica Delle Marche, Via Conca 71, 60126, Ancona, Italy.
Marche Polytechnic University · ITBiruni University · TRChinese University of Hong Kong · HKMarmara University · TRNg Teng Fong General Hospital · SGSaint Petersburg State Pediatric Medical University · RUSorbonne Université · FRUniversitat Autònoma de Barcelona · ESUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere has been a consistent increase in the last decades in prevalence of renal stones in elderly.

aimsTo evaluate outcomes of retrograde intrarenal surgery (RIRS) for renal stones in elderly and factors associated with postoperative complications and residual fragments (RFs).

methodsData from 12 centers were retrospectively reviewed. INCLUSION CRITERIA: ≥ 75 years, renal stones only, normal renal anatomy. Patients were divided into three groups; Group 1: patients aged 75-79 years; Group 2: age 80-84 years; Group 3: age ≥ 85 years. Multivariable logistic regression analyses were performed to assess factors associated with perioperative complications, sepsis, and RFs.

results366 patients were included. There were 189 patients in Group 1, 113 in Group 2, and 64 in Group 3. There was no difference between groups regarding stone features and total surgical time. Median length of stay was significantly longer in Group 3 (6.0 days, vs 2.0 days in Group 2 vs 2.5 days in Group 1, p = 0.043). There was no significant difference in postoperative complications and RFs between the groups. At multivariable logistic regression analysis, female gender (OR 2.82) and maximum stone diameter (OR 1.14) were associated with higher odds of sepsis, while surgical time (OR 1.12) and the use of a reusable ureteroscope (OR 6.51) with overall complications. Stone size (OR 1.23) was associated with higher odds of RFs.

conclusionRIRS showed safety and efficacy for kidney stones in elderly patients. Surgical time should be kept as short as possible to avoid higher odds of postoperative complications, particularly in females.

Indexed as

Kidney CalculiSepsisAgedFemaleHumansPostoperative ComplicationsRegistriesRetrospective StudiesTreatment OutcomeUreteroscopesUreteroscopyElderlyFlexible ureteroscopyLaserRenal stonesRetrograde intrarenal surgery

Identifiers

PMID37682489
PMCPMC10627914
OpenAlexW4386530300

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.