Evidence map›Paper›PMID 37682337›Full record

ArticleSkeletal radiology2024

Association of anatomical variants of the sacroiliac joint with bone marrow edema in patients with axial spondyloarthritis.

Elke Vereecke, Lennart Jans, Nele Herregods, Min Chen, Jacob L Jaremko, Frederiek Laloo, Philippe Carron, Gaëlle Varkas, Manouk de Hooge, Filip Van den Bosch and 2 more

Abstract read
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In one paragraph

Article in Skeletal radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Observational
  5. Article
  6. When it is not sacroiliitis.Skeletal radiology · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. The sacroiliac joint across ages - what is normal?Therapeutic advances in musculoskeletal disease · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Elke VereeckeDepartment of Radiology, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium. elke.vereecke@uzgent.be.ORCID http://orcid.org/0000-0002-1670-9431
Lennart JansDepartment of Radiology, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium.
Nele HerregodsDepartment of Radiology, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium.
Min ChenDepartment of Radiology, Peking University Shenzhen Hospital, Shenzhen, China.
Jacob L JaremkoDepartment of Radiology and Diagnostic Imaging, Faculty of Medicine and Dentistry, University of Alberta Hospital, Edmonton, AB, Canada.
Frederiek LalooDepartment of Radiology, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium.
Philippe CarronDepartment of Internal Medicine and Pediatrics, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
Gaëlle VarkasDepartment of Rheumatology, Ghent University Hospital, Ghent, Belgium.
Manouk de HoogeDepartment of Rheumatology, Ghent University Hospital, Ghent, Belgium.
Filip Van den BoschDepartment of Internal Medicine and Pediatrics, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
Dirk ElewautDepartment of Internal Medicine and Pediatrics, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
Lieve MorbéeDepartment of Radiology, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium.
Ghent University Hospital · BEAlberta Hospital Edmonton · CAPeking University Shenzhen Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the prevalence of sacroiliac joint variants in patients with axial spondyloarthritis (axSpA) using MRI-based synthetic CT images and to evaluate their relationships with the presence of bone marrow edema, as this may potentially complicate diagnosing active sacroiliitis on MRI in patients with suspected axSpA.

methods172 patients were retrospectively included. All patients underwent MRI because of clinical suspicion of sacroiliitis. The diagnosis of axSpA was made by a tertiary hospital rheumatologist. Two readers independently determined the presence of bone marrow edema and the presence of one or more of the nine known sacroiliac joint (SIJ) variants.

resultsSIJ variants were common in axSpA patients (82.9%) and the non-SpA group (85.4%); there were no significant differences in prevalence. Bone marrow edema was frequently found in axSpA (86.8%) and non-SpA patients (34%). AxSpA patients with SIJ variants (except for accessory joint) demonstrated 4 to 10 times higher odds for bone marrow edema, however not statistically significant. The more variants were present in this group, the higher the chance of bone marrow edema. However, some multicollinearity cannot be excluded, since bone marrow edema is very frequent in the axSpA group by definition.

conclusionSIJ variants are common in axSpA and non-SpA patients. SIJ variants were associated with higher prevalence of bone marrow edema in axSpA patients, potentially due to altered biomechanics, except for accessory joint which may act as a stabilizer.

Indexed as

Axial SpondyloarthritisBone Marrow DiseasesSacroiliitisSpondylarthritisBone MarrowEdemaHumansMagnetic Resonance ImagingRetrospective StudiesSacroiliac JointAnatomic VariationMagnetic Resonance ImagingSacroiliac JointSpondyloarthritisSpondyloarthropathies

Identifiers

PMID37682337
OpenAlexW4386530957

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.