Evidence map›Paper›PMID 37682335›Full record

SynthesisGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2024

Effects of firsthand tobacco smoking on retinal vessel caliber: a systematic review and meta-analysis.

Vincent L Yuen, Xiu Juan Zhang, Xiangtian Ling, Yuzhou Zhang, Ka Wai Kam, Li Jia Chen, Patrick Ip, Clement C Tham, Carol Y Cheung, Chi Pui Pang and 1 more

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Vincent L YuenDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Xiu Juan ZhangDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Xiangtian LingDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Yuzhou ZhangDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Ka Wai KamDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Li Jia ChenDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Patrick IpDepartment of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong SAR, China.
Clement C ThamDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Carol Y CheungDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Chi Pui PangDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Jason C YamDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China. yamcheuksing@cuhk.edu.hk.ORCID http://orcid.org/0000-0002-2156-1486

Funding

Chinese University of Hong Kong 178662514Chinese University of Hong Kong 4054121Chinese University of Hong Kong 4054193Chinese University of Hong Kong 4054199Chinese University of Hong Kong 4054634Collaborative Research Fund C7149-20GHealth and Medical Research Fund 07180826Health and Medical Research Fund 5160836Innovation and Technology Fund 7010590National Natural Science Foundation of China 8217040098Research Grants Council, University Grants Committee 14103419Research Grants Council, University Grants Committee 14111515UBS Optimus Foundation 8984
6 · The paper itself

Abstract

purposeTo review the effects of firsthand tobacco smoking on central retinal arteriolar equivalent (CRAE) and central retinal venular equivalent (CRVE) of firsthand tobacco smokers.

methodsWe performed a search on EMBASE and PubMed for studies up to 15

resultsIn this meta-analysis, 7431 nonsmokers, 2448 current smokers and 5786 former smokers, as well as 7404 nonsmokers, 2430 current smokers and 5763 former smokers were included in CRAE and CRVE analysis respectively. Nonsmokers had narrower CRVE (Weighted mean difference [WMD], -12.15; 95% CI, -17.33 - -6.96) and CRAE (WMD, -4.77; 95% CI, -7.96 - -1.57) than current smokers, and narrower CRVE (WMD, -3.08; 95% CI, -6.06 - -0.11) than former smokers. Current smokers had wider CRVE (WMD, 10.42; 95% CI, 7.80 - 13.04) and CRAE (WMD, 7.05; 95% CI, 6.65 - 7.46) than former smokers. Subgroup analysis and sensitivity analysis were performed.

conclusionFirsthand tobacco smoking resulted in wider CRAE and CRVE in current and former smokers, particularly in CRVE, and such changes may not be reversible after smoking cessation. Therefore, retinal vessel caliber may reflect the effects of firsthand tobacco smoking and be used to estimate the risk of cardiovascular diseases.

Indexed as

Retinal VesselsHumansRetinal DiseasesRisk FactorsTobacco Smoke PollutionTomography, Optical CoherenceTobacco Smoke PollutionCentral retinal arteriolar equivalentCentral retinal venular equivalentChildrenFirsthand tobacco smokingRetinal vessel caliber

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.