Evidence map›Paper›PMID 37682299›Full record

ArticleApplied microbiology and biotechnology2023

Efficient production of α-ketoglutaric acid using an economical double-strain cultivation and catalysis system.

Kun Liu, Yan Liu, Xiangfei Li, Xiushan Zhang, Zhenglian Xue, Ming Zhao

Abstract read
PubMed Publisher
In one paragraph

Article in Applied microbiology and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kun Liu *Anhui Engineering Laboratory for Industrial Microbiology Molecular Breeding, College of Biology and Food Engineering, Anhui Polytechnic University, Wuhu, 241000, China.
Yan Liu *Anhui Engineering Laboratory for Industrial Microbiology Molecular Breeding, College of Biology and Food Engineering, Anhui Polytechnic University, Wuhu, 241000, China.
Xiangfei LiAnhui Engineering Laboratory for Industrial Microbiology Molecular Breeding, College of Biology and Food Engineering, Anhui Polytechnic University, Wuhu, 241000, China.
Xiushan ZhangAnhui Engineering Laboratory for Industrial Microbiology Molecular Breeding, College of Biology and Food Engineering, Anhui Polytechnic University, Wuhu, 241000, China.
Zhenglian XueAnhui Engineering Laboratory for Industrial Microbiology Molecular Breeding, College of Biology and Food Engineering, Anhui Polytechnic University, Wuhu, 241000, China. xuezl@ahpu.edu.cn.
Ming ZhaoAnhui Engineering Laboratory for Industrial Microbiology Molecular Breeding, College of Biology and Food Engineering, Anhui Polytechnic University, Wuhu, 241000, China. zhaom@mail.ahpu.edu.cn.ORCID http://orcid.org/0000-0003-2492-4606
Anhui Polytechnic University · CN

Funding

Science and Technology Plan Project of Wuhu 2022jc19Science Foundation for The Excellent Youth Scholars of Anhui Provincial Education Department 2022AH030097
6 · The paper itself

Abstract

The whole-cell catalysis strategy of alpha-ketoglutaric acid (α-KG) production from L-glutamic acid (L-Glu) using recombinant Escherichia coli, in which L-glutamate oxidase (LGox) was over-expressed, has replaced the traditional chemical synthesis strategy. However, large amounts of toxic by-product, H

Indexed as

Escherichia coliKetoglutaric AcidsStreptomycesAmino Acid OxidoreductasesBiocatalysisCatalysisFermentationGlutamic AcidMetabolic EngineeringStreptomyces lividansAmino Acid OxidoreductasesGlutamic AcidKetoglutaric AcidsL-glutamate oxidaseAlpha-ketoglutaric acidBiocatalysisDouble-strain cultivationLow-dosage-IPTG

Identifiers

PMID37682299
OpenAlexW4386530164

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.