Evidence map›Paper›PMID 37682209›Full record

ArticleThe journal of extra-corporeal technology2023

Indexed oxygen delivery during pediatric cardiopulmonary bypass is a modifiable risk factor for postoperative acute kidney injury.

Molly Dreher, Jungwon Min, Constantine Mavroudis, Douglas Ryba, Svetlana Ostapenko, Richard Melchior, Tami Rosenthal, Muhammad Nuri, Joshua Blinder

Open access · diamondAbstract read
In one paragraph

Article in The journal of extra-corporeal technology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
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  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Molly DreherDepartment of Cardiovascular Perfusion, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Jungwon MinDepartment of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.ORCID 0000-0002-5518-9782
Constantine MavroudisChildren's Hospital of Philadelphia, Cardiac Center, Division of Cardiothoracic Surgery, Philadelphia, PA 19104, USA.
Douglas RybaInformation Services Department, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Svetlana OstapenkoDepartment of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Richard MelchiorDepartment of Cardiovascular Perfusion, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Tami RosenthalDepartment of Cardiovascular Perfusion, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Muhammad NuriChildren's Hospital of Philadelphia, Cardiac Center, Division of Cardiothoracic Surgery, Philadelphia, PA 19104, USA.
Joshua BlinderStanford University School of Medicine, Lucile Packard Children's Hospital, Department of Pediatrics, Division of Pediatric Cardiology, Palo Alto, CA 94304, USA.
Children's Hospital of Philadelphia · USLucile Packard Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute kidney injury after pediatric cardiac surgery is a common complication with few established modifiable risk factors. We sought to characterize whether indexed oxygen delivery during cardiopulmonary bypass was associated with postoperative acute kidney injury in a large pediatric cohort.

methodsThis was a retrospective analysis of patients under 1 year old undergoing cardiac surgery with cardiopulmonary bypass between January 1, 2013, and January 1, 2020. Receiver operating characteristic curves across values ranging from 260 to 400 mL/min/m

resultsWe included 980 patients with acute kidney injury occurring in 212 (21.2%). After adjusting for covariates associated with acute kidney injury, an indexed oxygen delivery threshold of 340 mL/min/m

conclusionIndexed oxygen delivery during cardiopulmonary bypass is a modifiable variable independently associated with postoperative acute kidney injury in specific pediatric populations. Strategies aimed at maintaining oxygen delivery greater than 340 mL/min/m

Indexed as

Acute Kidney InjuryCardiopulmonary BypassChildHumansInfantInfant, NewbornOxygenRetrospective StudiesRisk FactorsOxygenAcute kidney injuryCardiac surgeryCardiopulmonary bypassIndexed oxygen deliveryPediatric

Identifiers

PMID37682209
PMCPMC10487348
OpenAlexW4384306063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.