Evidence map›Paper›PMID 37682108›Full record

ArticleBioinformatics (Oxford, England)2023

DrForna: visualization of cotranscriptional folding.

Anda Ramona Tănasie, Peter Kerpedjiev, Stefan Hammer, Stefan Badelt

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anda Ramona TănasieInstitute of Discrete Mathematics and Geometry, Technische Universität Wien, Vienna, Austria.ORCID 0000-0001-8600-1765
Peter KerpedjievDepartment of Theoretical Chemistry, University of Vienna, Vienna, Austria.ORCID 0000-0002-0454-1803
Stefan HammerDepartment of Theoretical Chemistry, University of Vienna, Vienna, Austria.ORCID 0000-0002-0716-8063
Stefan BadeltDepartment of Theoretical Chemistry, University of Vienna, Vienna, Austria.ORCID 0000-0003-2636-5801

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

motivationUnderstanding RNA folding at the level of secondary structures can give important insights concerning the function of a molecule. We are interested to learn how secondary structures change dynamically during transcription, as well as whether particular secondary structures form already during or only after transcription. While different approaches exist to simulate cotranscriptional folding, the current strategies for visualization are lagging behind. New, more suitable approaches are necessary to help with exploring the generated data from cotranscriptional folding simulations.

resultsWe present DrForna, an interactive visualization app for viewing the time course of a cotranscriptional RNA folding simulation. Specifically, users can scroll along the time axis and see the population of structures that are present at any particular time point. AVAILABILITY AND IMPLEMENTATION: DrForna is a JavaScript project available on Github at https://github.com/ViennaRNA/drforna and deployed at https://viennarna.github.io/drforna.

Indexed as

RNA FoldingComputer Simulation

Identifiers

PMID37682108
PMCPMC10504468

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.