Evidence map›Paper›PMID 37682015›Full record

ArticleJournal of veterinary internal medicine

Longitudinal examination of urine pH, specific gravity, protein, culture, and antimicrobial resistance profiles in healthy dogs.

Andrew McGlynn, Ryan Mrofchak, Rushil Madan, Christopher Madden, Mohammad Jawad Jahid, Dixie Mollenkopf, Thomas Wittum, Sheryl S Justice, Adam Rudinsky, Jessica Hokamp and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Andrew McGlynnCollege of Veterinary Medicine, The Ohio State University, Columbus, Ohio, USA.
Ryan MrofchakDepartment of Veterinary Preventive Medicine, The Ohio State University, Columbus, Ohio, USA.
Rushil MadanCollege of Veterinary Medicine, The Ohio State University, Columbus, Ohio, USA.
Christopher MaddenDepartment of Veterinary Preventive Medicine, The Ohio State University, Columbus, Ohio, USA.
Mohammad Jawad JahidDepartment of Veterinary Preventive Medicine, The Ohio State University, Columbus, Ohio, USA.
Dixie MollenkopfDepartment of Veterinary Preventive Medicine, The Ohio State University, Columbus, Ohio, USA.
Thomas WittumDepartment of Veterinary Preventive Medicine, The Ohio State University, Columbus, Ohio, USA.
Sheryl S JusticeCollege of Nursing, The Ohio State University, Columbus, Ohio, USA.
Adam RudinskyDepartment of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0001-5369-3152
Jessica HokampDepartment of Veterinary Biosciences, The Ohio State University, Columbus, Ohio, USA.
Vanessa HaleDepartment of Veterinary Preventive Medicine, The Ohio State University, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0002-8531-7001
The Ohio State University · USOhio Department of Health · US

Funding

Short Trem Research Training for Veterinary StudentsT35OD010977 · OD · OHIO STATE UNIVERSITY · PI Christine A Petersen · 2012 to 2026
$1.1M
NIH HHS T35 OD010977The Muffin Sniadowski Student Research Endowment FundThe Ohio State University College of Veterinary Medicine Canine Funds
6 · The paper itself

Abstract

backgroundUrine is routinely evaluated in dogs to assess health. Reference ranges for many urine properties are well established, but the scope of variation in these properties over time within healthy dogs is not well characterized.

objectivesLongitudinally characterize urine properties in healthy dogs over 3 months. ANIMALS: Fourteen healthy client-owned dogs.

methodsIn this prospective study, dogs were evaluated for health; then, mid-stream free-catch urine was collected from each dog at 12 timepoints over 3 months. Urine pH, urine specific gravity (USG), protein, cultures, and antimicrobial resistance profiles were assessed at each timepoint.

resultsUrine pH varied within and between dogs over time (Friedman's test: within P = .03; between P < .005). However, USG, protein, and bacterial diversity of urine were consistent within dogs over time, and only varied between dogs (Kruskal-Wallis: between all P < .005). Antimicrobial resistant isolates were identified in 12 out of 14 dogs with 34 of 48 of the isolates demonstrating resistance to amoxicillin. CONCLUSIONS AND CLINICAL IMPORTANCE: Urine pH should be assessed at multiple timepoints via pH meter before making clinical decisions. Mid-stream free-catch urine with high concentrations of bacteria (>10

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialAmoxicillinAnimalsDogsHumansHydrogen-Ion ConcentrationProspective StudiesSpecific GravityAmoxicillinAnti-Bacterial Agentsantimicrobial resistancecanineurine cultureurine proteinurine specific gravity

Identifiers

PMID37682015
PMCPMC10658500
OpenAlexW4386530250

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.