Evidence map›Paper›PMID 37681961›Full record

ArticleApplied and environmental microbiology2023

An underlying mechanism for MleR activating the malolactic enzyme pathway to enhance acid tolerance in

Ran Huan, Zeyu Cao, Zhengyuan Zhai, Xin Feng, Yanling Hao

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ran HuanCollege of Food Science and Nutritional Engineering, China Agricultural University , Beijing, China.
Zeyu CaoCollege of Food Science and Nutritional Engineering, China Agricultural University , Beijing, China.
Zhengyuan ZhaiCollege of Food Science and Nutritional Engineering, China Agricultural University , Beijing, China.
Xin FengCollege of Food Science and Nutritional Engineering, China Agricultural University , Beijing, China.
Yanling HaoFood Laboratory of Zhongyuan , Luohe, Henan, China.ORCID 0000-0002-2562-6849
China Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tolerance to acid stress is a crucial property of probiotics against gastric acids. The malolactic enzyme pathway is one of the most important acid resistance systems in lactic acid bacteria. It has been reported that the malolactic enzyme pathway was regulated by the transcriptional regulator, MleR. However, regulatory mechanisms underlying malolactic enzyme pathway to cope with acid stress remain unknown. In this study, the acid tolerance ability of the

Indexed as

Lacticaseibacillus paracaseiAcidsHumansLacticaseibacillusMalate DehydrogenaseMalatesAcidsMalate DehydrogenaseMalatesmalic acidmalolactic enzymeacid stressLacticaseibacillus paracasei L9LysR-type transcriptional regulatormalolactic enzyme pathwayMleR

Identifiers

PMID37681961
PMCPMC10537729
OpenAlexW4386530040

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.