Evidence map›Paper›PMID 37681956›Full record

ArticleJournal of virology2023

Deletion of a 7-amino-acid region in the porcine epidemic diarrhea virus envelope protein induces higher type I and III interferon responses and results in attenuation

Zhiwei Li, Zhiqian Ma, Weiguo Han, Chuanzhe Chang, Yang Li, Xuyang Guo, Zifang Zheng, Yingtong Feng, Lele Xu, Haixue Zheng and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Zhiwei Li *College of Veterinary Medicine, Northwest A&F University , Yangling, Shaanxi, China.
Zhiqian Ma *State Key Laboratory for Animal Disease Control and Prevention, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, College of Veterinary Medicine, Lanzhou University , Lanzhou, Gansu, China.
Weiguo HanCollege of Veterinary Medicine, Northwest A&F University , Yangling, Shaanxi, China.
Chuanzhe ChangState Key Laboratory for Animal Disease Control and Prevention, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, College of Veterinary Medicine, Lanzhou University , Lanzhou, Gansu, China.
Yang LiState Key Laboratory for Animal Disease Control and Prevention, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, College of Veterinary Medicine, Lanzhou University , Lanzhou, Gansu, China.
Xuyang GuoCollege of Veterinary Medicine, Northwest A&F University , Yangling, Shaanxi, China.
Zifang ZhengState Key Laboratory for Animal Disease Control and Prevention, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, College of Veterinary Medicine, Lanzhou University , Lanzhou, Gansu, China.
Yingtong FengCollege of Veterinary Medicine, Northwest A&F University , Yangling, Shaanxi, China.
Lele XuCollege of Veterinary Medicine, Northwest A&F University , Yangling, Shaanxi, China.
Haixue ZhengState Key Laboratory for Animal Disease Control and Prevention, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, College of Veterinary Medicine, Lanzhou University , Lanzhou, Gansu, China.
Xinglong WangCollege of Veterinary Medicine, Northwest A&F University , Yangling, Shaanxi, China.
Shuqi XiaoCollege of Veterinary Medicine, Northwest A&F University , Yangling, Shaanxi, China.ORCID 0000-0002-6468-2608
Lanzhou Veterinary Research Institute · CNNorthwest A&F University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porcine epidemic diarrhea virus (PEDV) leads to enormous economic losses for the pork industry. However, the commercial vaccines failed to fully protect against the epidemic strains. Previously, the rCH/SX/2016-S

Indexed as

Coronavirus InfectionsPorcine epidemic diarrhea virusSwine DiseasesViral Envelope ProteinsAnimalsInterferonsRNASequence DeletionSwineVaccines, AttenuatedInterferonsRNAVaccines, AttenuatedViral Envelope ProteinscoronavirusenvelopeinterferonPEDVreverse genetic analysisthe molecular basis of the attenuation of PEDVvirulence factor

Identifiers

PMID37681956
PMCPMC10537754
OpenAlexW4386530367

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.