Evidence map›Paper›PMID 37681898›Full record

ArticleCells2023

Polycystin-1 Interacting Protein-1 (CU062) Interacts with the Ectodomain of Polycystin-1 (PC1).

Wendy A Lea, Thomas Winklhofer, Lesya Zelenchuk, Madhulika Sharma, Jessica Rossol-Allison, Timothy A Fields, Gail Reif, James P Calvet, Jason L Bakeberg, Darren P Wallace and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Wendy A LeaDepartment of Nephrology and Hypertension, The Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, 3901 Rainbow Blvd., Mail Stop 3018, KS 66160, USA.ORCID 0000-0002-2101-0449
Thomas WinklhoferDepartment of Nephrology and Hypertension, The Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, 3901 Rainbow Blvd., Mail Stop 3018, KS 66160, USA.ORCID 0000-0002-6126-2288
Lesya ZelenchukDepartment of Nephrology and Hypertension, The Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, 3901 Rainbow Blvd., Mail Stop 3018, KS 66160, USA.ORCID 0000-0001-8256-187X
Madhulika SharmaDepartment of Nephrology and Hypertension, The Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, 3901 Rainbow Blvd., Mail Stop 3018, KS 66160, USA.ORCID 0000-0001-7488-5444
Jessica Rossol-AllisonPromega Corporation, 2800 Woods Hollow Road, Madison, WI 53711, USA.ORCID 0000-0003-0208-5952
Timothy A FieldsDepartment of Pathology & Laboratory Medicine, University of Kansas Medical Center, 3901 Rainbow Blvd., Mail Stop 3062, Kansas City, KS 66160, USA.ORCID 0000-0003-0665-370X
Gail ReifDepartment of Nephrology and Hypertension, The Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, 3901 Rainbow Blvd., Mail Stop 3018, KS 66160, USA.ORCID 0000-0001-5704-3333
James P CalvetDepartment of Nephrology and Hypertension, The Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, 3901 Rainbow Blvd., Mail Stop 3018, KS 66160, USA.ORCID 0000-0001-5928-9820
Jason L BakebergDepartment of Nephrology and Hypertension, The Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, 3901 Rainbow Blvd., Mail Stop 3018, KS 66160, USA.ORCID 0009-0007-8593-365X
Darren P WallaceDepartment of Nephrology and Hypertension, The Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, 3901 Rainbow Blvd., Mail Stop 3018, KS 66160, USA.ORCID 0000-0003-4616-7669
Christopher J WardDepartment of Nephrology and Hypertension, The Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, 3901 Rainbow Blvd., Mail Stop 3018, KS 66160, USA.ORCID 0000-0002-2507-9398
University of Kansas Medical Center · USPromega (United States) · US

Funding

Polycystin Function Resource Development CoreU54DK126126 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI DARREN P. WALLACE · 2020 to 2026
$5.8M
Human-specific Abnormal Alternative Splicing of the Wild-type PKD1 Gene Induces Premature Termination of Polycystin-1R01DK122205 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI WARD, CHRISTOPHER J · 2020 to 2024
$1.7M
Super resolution microscope for the imaging core facilityS10OD023625 · OD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI NISHIMUNE, HIROSHI · 2019 to 2019
$987k
NIDDK NIH HHS R01 DK122205NIDDK NIH HHS U54 DK126126NIH HHS S10 OD023625
6 · The paper itself

Abstract

The

Indexed as

Extracellular VesiclesPolycystic Kidney, Autosomal DominantGenes, RegulatorHumansMitochondriaTRPP Cation ChannelsTRPP Cation Channelsautosomal dominant polycystic kidney disease (ADPKD)C21orf62collecting ductexosomesligandmigrasomespolycystin-2primary ciliaproximal tubule

Identifiers

PMID37681898
PMCPMC10487028
OpenAlexW4386255144

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.