Evidence map›Paper›PMID 37681866›Full record

ArticleCells2023

Brain Metabolomics in Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS).

Maria Jimena Salcedo-Arellano, Michael D Johnson, Yingratana A McLennan, Ye Hyun Hwang, Pablo Juarez, Erin Lucille McBride, Adriana P Pantoja, Blythe Durbin-Johnson, Flora Tassone, Randi J Hagerman and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Studies on copper (II) interaction with the (CCG)Journal of Alzheimer's disease reports
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Maria Jimena Salcedo-ArellanoDepartment of Pathology and Laboratory Medicine, UC Davis School of Medicine, Sacramento, CA 95817, USA.ORCID 0000-0002-2412-9146
Michael D JohnsonDepartment of Pathology and Laboratory Medicine, UC Davis School of Medicine, Sacramento, CA 95817, USA.
Yingratana A McLennanDepartment of Pathology and Laboratory Medicine, UC Davis School of Medicine, Sacramento, CA 95817, USA.ORCID 0000-0001-8272-2012
Ye Hyun HwangDepartment of Biochemistry and Molecular Medicine, UC Davis School of Medicine, Sacramento, CA 95817, USA.
Pablo JuarezDepartment of Pathology and Laboratory Medicine, UC Davis School of Medicine, Sacramento, CA 95817, USA.
Erin Lucille McBrideDepartment of Pathology and Laboratory Medicine, UC Davis School of Medicine, Sacramento, CA 95817, USA.
Adriana P PantojaDepartment of Pathology and Laboratory Medicine, UC Davis School of Medicine, Sacramento, CA 95817, USA.
Blythe Durbin-JohnsonDivision of Biostatistics, Department of Public Health Sciences, UC Davis School of Medicine, Sacramento, CA 95817, USA.
Flora TassoneMedical Investigation of Neurodevelopmental Disorders (MIND) Institute, University of California Davis, Sacramento, CA 95616, USA.
Randi J HagermanMedical Investigation of Neurodevelopmental Disorders (MIND) Institute, University of California Davis, Sacramento, CA 95616, USA.
Verónica Martínez-CerdeñoDepartment of Pathology and Laboratory Medicine, UC Davis School of Medicine, Sacramento, CA 95817, USA.
Shriners Hospitals for Children - Northern California · USUniversity of California, Davis · US

Funding

GENOTYPE/PHENOTYPE RELATIONSHIPS IN FRAGILE X FAMILIESR01HD036071 · NICHD · UNIVERSITY OF CALIFORNIA DAVIS · PI PAUL J HAGERMAN, RANDI J. HAGERMAN · 1998 to 2026
$13.8M
Research Project: Pathologic Significance of Maternal AutoantibodiesP50HD103526 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEONARD J. ABBEDUTO, Melissa Dawn Bauman · 2020 to 2026
$9.7M
Fragile X-associated tremor/ataxia syndrome (FXTAS) pathology and anatomy: imaging and clinical correlatesR01NS107131 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MARTINEZ-CERDENO, VERONICA · 2018 to 2022
$2.6M
NICHD NIH HHS P50 HD103526NICHD NIH HHS R01 HD036071NINDS NIH HHS R01 NS107131
6 · The paper itself

Abstract

The course of pathophysiological mechanisms involved in fragile X-associated tremor/ataxia syndrome (FXTAS) remains largely unknown. Previous proteomics and metabolomics studies conducted in blood samples collected from

Indexed as

BrainTremorAtaxiaCytidineCytosineFragile X Messenger Ribonucleoprotein 1Fragile X SyndromeGuanineHumansMetabolomicsCytidineCytosineFMR1 protein, humanFragile X Messenger Ribonucleoprotein 1GuanineFMR1FXTASmetabolomicsneurodegeneration

Identifiers

PMID37681866
PMCPMC10487256
OpenAlexW4386135181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.