Evidence map›Paper›PMID 37681852›Full record

ReviewCells2023

Pathophysiology of Disseminated Intravascular Coagulation in Sepsis: A Clinically Focused Overview.

Ahsanullah Unar, Lorenzo Bertolino, Fabian Patauner, Raffaella Gallo, Emanuele Durante-Mangoni

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 52 citations in OpenAlex.

  1. Platelet subpopulations and contribution to hemostasis.Blood science (Baltimore, Md.) · 2026
    Review
  2. Article
  3. Article
  4. Selected Cannabinoids, Cannabimimetic Agents andPharmaceuticals (Basel, Switzerland) · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Infection and drug resistance · 2026
    Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Roles of endothelial cells during infection.Current opinion in immunology · 2025
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ahsanullah UnarDepartment of Precision Medicine, University of Campania 'L. Vanvitelli', 80138 Naples, Italy.ORCID 0000-0002-8533-0855
Lorenzo BertolinoDepartment of Precision Medicine, University of Campania 'L. Vanvitelli', 80138 Naples, Italy.
Fabian PataunerDepartment of Precision Medicine, University of Campania 'L. Vanvitelli', 80138 Naples, Italy.ORCID 0000-0001-8556-9180
Raffaella GalloDepartment of Precision Medicine, University of Campania 'L. Vanvitelli', 80138 Naples, Italy.ORCID 0000-0002-5903-9191
Emanuele Durante-MangoniDepartment of Precision Medicine, University of Campania 'L. Vanvitelli', 80138 Naples, Italy.ORCID 0000-0002-5381-3537
University of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis is a major global health problem that results from a dysregulated and uncontrolled host response to infection, causing organ failure. Despite effective anti-infective therapy and supportive treatments, the mortality rate of sepsis remains high. Approximately 30-80% of patients with sepsis may develop disseminated intravascular coagulation (DIC), which can double the mortality rate. There is currently no definitive treatment approach for sepsis, with etiologic treatment being the cornerstone of therapy for sepsis-associated DIC. Early detection, diagnosis, and treatment are critical factors that impact the prognosis of sepsis-related DIC. Over the past several decades, researchers have made continuous efforts to better understand the mechanisms of DIC in sepsis, as well as improve its quantitative diagnosis and treatment. This article aims to provide a comprehensive overview of the current understanding of sepsis-related DIC, focusing on common causes and diagnoses, with the goal of guiding healthcare providers in the care of patients with sepsis.

Indexed as

Disseminated Intravascular CoagulationSepsisHealth PersonnelHumansdisseminated intravascular coagulationimmune cellmechanismpathogenesisplateletssepsistherapythrombosistreatment

Identifiers

PMID37681852
PMCPMC10486945
OpenAlexW4386050759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.