Evidence map›Paper›PMID 37681518›Full record

ArticleJournal of the American Heart Association2023

Association of Magnesium Depletion Score With Cardiovascular Disease and Its Association With Longitudinal Mortality in Patients With Cardiovascular Disease.

Liu Ye, Cheng Zhang, Qin Duan, Yue Shao, Jianzhong Zhou

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06726460 recruitingnot on this mapstarted 2024, after this paper: background citation

Validation of the Accuracy of a Novel POCT Dry Electrolyte Analysis System in the Acute Care Setting: A Cross-Sectional Study

TypeobservationalSponsorZhujiang HospitalRan2024 to 2025Enrolled200ConditionsElectrolyte Disorder, Arrhythmia, StrokeArmsNova Stat Profile pHOx Ultra Analyzer System(Nova), Novel POCT dry electrolyte analysis system(P1)
NCT06891846 completednot on this mapstarted 2025, after this paper: background citation

Evaluation of the Relationship Between Magnesium Depletion Score And Socket Healing Following Tooth Extraction

Typeobservational_patient_registrySponsorSaglik Bilimleri UniversitesiRan2025 to 2025Enrolled111ConditionsWound Healing, Magnesium Level, Wisdom Tooth Removal
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 61 citations in OpenAlex.

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  12. Understanding Renal Tubular Function: Key Mechanisms, Clinical Relevance, and Comprehensive Urine Assessment.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Liu YeThe First Branch The First Affiliated Hospital of Chongqing Medical University Chongqing China.ORCID 0000-0001-7526-6661
Cheng ZhangDepartment of Cardiothoracic Surgery The First Affiliated Hospital of Chongqing Medical University Chongqing China.
Qin DuanThe First Branch The First Affiliated Hospital of Chongqing Medical University Chongqing China.
Yue ShaoDepartment of Cardiothoracic Surgery The First Affiliated Hospital of Chongqing Medical University Chongqing China.
Jianzhong ZhouDepartment of Cardiology The First Affiliated Hospital of Chongqing Medical University Chongqing China.ORCID 0009-0008-1002-2752
The Affiliated Yongchuan Hospital of Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Dietary magnesium and serum magnesium play an important part in cardiovascular disease (CVD). However, the association between magnesium depletion score (MDS) and CVD development and prognosis remains unclear. This analysis examines the cross-sectional relationship between MDS and CVD, and the longitudinal association between MDS and all-cause and CVD mortality in individuals with CVD. Methods and Results In all, 42 711 individuals were selected from the National Health and Nutrition Examination Survey, including 5015 subjects with CVD. The association between MDS and total and individual CVDs was examined using the survey-weighted multiple logistic regression analysis. Among 5011 patients with CVD, 2285 and 927 participants were recorded with all-cause and CVD deaths, respectively. We applied survey-weighted Cox proportional hazards regression analyses to investigate the impact of MDS on the mortality of individuals with CVD. The CVD group had higher MDS levels than the non-CVD groups. After controlling all confounding factors, individuals with MDS of 2 and ≥3 had higher odds of total CVD and specific CVD than those with MDS of 0. Besides, each 1-unit increase in MDS was strongly related to the risk of total CVD and specific CVD. The relationship between MDS and total CVD was stable and significant in all subgroups. The fully adjusted Cox regression model indicated that high MDS, irrespective of MDS as a categorical or continuous variable, was significantly associated with an elevated risk of all-cause and CVD deaths. Conclusions MDS is a vital risk factor for the prevalence and mortality of individuals with CVD.

Indexed as

Cardiovascular DiseasesMagnesiumHumansNutrition SurveysPatientsRisk FactorsMagnesiumall‐cause mortalitycardiovascular diseasecardiovascular mortalitymagnesium depletion scoreNHANES

Identifiers

PMID37681518
PMCPMC10547298
OpenAlexW4386530173

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.