Evidence map›Paper›PMID 37681353›Full record

ArticleJournal of periodontal & implant science2024

A large animal model of periodontal defects in bisphosphonate-related osteonecrosis of the jaw: a comparison of clinical and radiological findings.

Marius Otto, Andreas Neff, Thomas Ziebart, Frank Halling

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of periodontal & implant science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Marius OttoDepartment of Pediatric Surgery, Pediatric Urology and Pediatric Orthopedics, DRK Children's Hospital Siegen, Siegen, Germany.ORCID https://orcid.org/0000-0002-1622-4944
Andreas NeffDepartment of Oral and Maxillofacial Surgery, University Hospital Marburg, Marburg, Germany.ORCID https://orcid.org/0000-0001-5865-0020
Thomas ZiebartDepartment of Oral and Maxillofacial Surgery, University Hospital Marburg, Marburg, Germany.ORCID https://orcid.org/0000-0003-3296-7630
Frank HallingDepartment of Oral and Maxillofacial Surgery, University Hospital Marburg, Marburg, Germany.ORCID https://orcid.org/0000-0002-5207-412X
Philipps University of Marburg · DE

Funding

NIAID NIH HHS C-11-11-V
6 · The paper itself

Abstract

purposeThe objective of this study was to demonstrate the suitability of cone-beam computed tomography (CBCT) for

methodsHalves of the jaws of 9 Swiss mountain sheep, assigned to a control group (n=3), an osteoporosis group (n=3) and a zoledronate-exposed group (n=3), were examined. Clinical and radiological evaluations were conducted using CBCT imaging to assess whether periodontitis and bone defects were observed to a significant extent after surgical tooth extraction.

resultsIn contrast to the control and osteoporosis groups, the zoledronate group exhibited significant residual bone defects following tooth extraction (

conclusionsEvaluating residual defects in bone blocks from sheep using CBCT analysis was found to be as effective as a clinical examination conducted by specialists in oral and maxillofacial surgery. The strong correlation between radiological findings and clinical conditions suggests that CBCT may become increasingly important in the future, particularly in periodontological research related to BRONJ.

Indexed as

Animal modelsBisphosphonate-associated osteonecrosis of the jawCone-beam computed tomographyPeriodontitis

Identifiers

PMID37681353
PMCPMC11227933
OpenAlexW4385268032

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.