Evidence map›Paper›PMID 37681127›Full record

ArticleHeliyon2023

Encapsulation of alpha arbutin, a depigmenting agent, in nanosized ethosomes:

Haji Muhammad Shoaib Khan, Nishma Tanveer, Tahreem Arshad, Fatima Rasool, Mohammad N Uddin, Mohsin Kazi

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Formulation andACS omega · 2026
    Article
  3. Review
  4. Review
  5. Pre-treatment with caffeic acid-phthalimide prevents UVB-induced oxidative stress and cytotoxicity.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Frontiers in pharmacology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Haji Muhammad Shoaib KhanDepartment of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Punjab, 63100, Pakistan.
Nishma TanveerDepartment of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Punjab, 63100, Pakistan.
Tahreem ArshadDepartment of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Punjab, 63100, Pakistan.
Fatima RasoolUniversity College of Pharmacy, University of The Punjab, Lahore, Punjab, 05422, Pakistan.
Mohammad N UddinDepartment of Pharmaceutical Sciences, College of Pharmacy, Mercer University, Atlanta, GA 30341, USA.
Mohsin KaziDepartment of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box-2457, Riyadh 11451, Saudi Arabia.
Islamia University of Bahawalpur · PKKing Saud University · SAMercer University Health Sciences Center · USUniversity of the Punjab · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alpha arbutin is a skin-whitening agent in cosmetics. Structurally, it is 4-hydroxyphenyl-α-glucopyranoside. Ethosomes encourage the formation of lamellar-shaped vesicles with improved solubility and entrapment of whitening agents. The objective of this study was to fabricate an optimized nanostructured ethosomal gel loaded with alpha arbutin for the treatment of skin pigmentation. Different ethosomal suspensions of alpha arbutin were prepared by the cold method.

Indexed as

Alpha arbutinDepigmenting agentEntrapment efficiencyEthosomesMelanin

Identifiers

PMID37681127
PMCPMC10481281
OpenAlexW4386102074

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.