ArticleRespirology case reports2023
Tricky sepsis biomarker: Extremely high procalcitonin in squamous cell lung cancer with doubtful infection.
Article in Respirology case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- [Abnormally Elevated Procalcitonin in Stage IV Lung Adenocarcinoma with Neuroendocrine Differentiation: A Case Report and Literature Review].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2026Review
- Are Ki-67 and Procalcitonin Expression Levels Useful in Predicting the Biological Behavior of Hepatocellular Carcinoma After Liver Transplantation?Journal of clinical medicine · 2024Article
- Tricky sepsis biomarker: Extremely high procalcitonin in squamous cell lung cancer with doubtful infection.Respirology case reports · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Procalcitonin is a 116 amino acid polypeptide synthesized by the C-cells of the thyroid gland. Elevated serum procalcitonin levels are generally thought to be the result of systemic bacterial infection, but recent reviews have suggested an association between procalcitonin and patients with cancer. This case report discusses an illustrative case with elevated procalcitonin levels in a patient with squamous cell carcinoma and multiple metastases. The increase in procalcitonin in patients may be due to an inflammatory state in the tumour microenvironment. Elevated procalcitonin is associated with disease progression, the presence of metastases, and a poor prognosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.