Evidence map›Paper›PMID 37680811›Full record

ArticlePakistan journal of medical sciences

Effects of oxycodone hydrochloride sustained-release tablets and morphine hydrochloride sustained-release tablets on peripheral blood T cell levels in advanced lung squamous cell carcinoma with moderate to severe cancer pain.

Juan Yan, Zheng-Zheng Xie, Na Ma, Mao-Dong Zheng, Ting-Ting Qiao, Yu Wang

Open access · goldAbstract read
In one paragraph

Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Juan YanJuan Yan, Department of Pharmacy, The First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei,075000, China.
Zheng-Zheng XieZheng-zheng Xie Department of Pharmacy, Beijing Shijitan Hospital, Beijing,100038, China.
Na MaNa Ma Department of Pharmacy, Taian City Central Hospital, Taian, Shandong,271400, China.
Mao-Dong ZhengMao-dong Zheng, Department of Pharmacy, The First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei,075000, China.
Ting-Ting QiaoTing-ting Qiao, Department of Pharmacy, The First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei,075000, China.
Yu WangYu Wang, Department of Pharmacy, The First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei,075000, China.
Hebei North University · CNTaian City Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the effects of morphine hydrochloride sustained-release tablets and oxycodone hydrochloride sustained-release tablets on T-cell levels in advanced lung squamous cell carcinoma(LUSC) with moderate to severe cancer pain. Methods: A retrospective study was used, ninety-eight patients who were admitted to The First Affiliated Hospital of Hebei North University for treatment of advanced LUSC with moderate to severe cancer pain between January 2021 and December 2021 were randomized into two groups(n=49 each) using the sealed envelope system. The reference group was treated with morphine hydrochloride sustained-release tablets, while the experimental group received oxycodone hydrochloride sustained-release tablets to compare pain relief rates(PRRs), levels of T cells, pain intensity, et al. Blood samples were collected for lymphocyte levels by flow cytometry. Results: The experimental group had significantly higher level than the reference group( Conclusions: Oxycodone hydrochloride sustained-release tablets demonstrate desirable efficacy and safety in advanced LUSC with moderate to severe cancer pain by modulating T-cells in the body and improving the PRR.

Indexed as

Cancer PainLung Squamous Cell CarcinomaMorphine Hydrochloride Sustained-Release TabletOxycodone Hydrochloride Sustained-Release Tablet

Identifiers

PMID37680811
PMCPMC10480705
OpenAlexW4383668293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.