ArticlePakistan journal of medical sciences
Association of triglyceride glucose index and triglyceride HDL ratio with glucose levels, microvascular and macrovascular complications in Diabetes Mellitus Type-2.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 8 citations in OpenAlex.
- Association Between the Triglyceride-to-HDL Cholesterol Ratio and Glycemic Control in Patients with Type 2 Diabetes Mellitus: A Real-World Retrospective Study.Biomedicines · 2026Article
- Correlation Between Fasting Blood Glucose and Serum Lipid Profile and Lipid Ratios in Patients with Type 2 Diabetes Mellitus in Southern Thailand: A Cross-Sectional Study.Medical sciences (Basel, Switzerland) · 2026Article
- Article
- Correlation of differential expression of MEG3 lnc-RNA with biochemical parameters in Type-II diabetic patients with and without diabetic kidney disease.Pakistan journal of medical sciences · 2026Article
- Serum uric acid mediates the association between the estimated glucose disposal rate and chronic kidney disease in patients with diabetes or prediabetes: an analysis from NHANES 2005-2018.BMC endocrine disorders · 2025Article
- Can the triglyceride-glucose index predict stroke outcomes? A systematic review and meta-analysis.Pakistan journal of medical sciences · 2025Review
- Predictive value of triglyceride glucose index and systemic inflammation index for diabetic retinopathy in Type-2 diabetes.Pakistan journal of medical sciences · 2025Article
- Serum Isthmin-1 levels are positively correlated with macrovascular complications in type 2 diabetic patients.Frontiers in endocrinology · 2025Article
- Prognostic Value of Triglyceride Glucose Index in ST-Elevation Myocardial Infarction: A Key Predictor of Mortality and Thrombus Burden.Diagnostics (Basel, Switzerland) · 2024Article
- Inflammatory and Metabolic Predictors of Mortality in Pulmonary Thromboembolism: A Focus on the Triglyceride-Glucose Index and Pan-Immune Inflammation Value.Journal of clinical medicine · 2024Article
- Evaluation of Paraoxonase-1 Activity of Arylesterase and Lactonase and Their Correlation with Oxidative Stress in Children with Type 1 Diabetes Mellitus.Reports of biochemistry & molecular biology · 2024Article
- The Role of Triglyceride/HDL Ratio, Triglyceride-Glucose Index, and Pan-Immune-Inflammation Value in the Differential Diagnosis of Acute Coronary Syndrome and Predicting Mortality.Journal of clinical medicine · 2024Article
- Role of Triglyceride-Glucose Index in Type 2 Diabetes Mellitus and Its Complications.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Review
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To find out the role of triglyceride glucose index (TGI) and triglyceride HDL ratio (THR) as predictors of insulin resistance and control of glucose status in type two diabetes mellitus (T2DM). Method: This cross-sectional study was conducted in Dr. Akbar Niazi Teaching Hospital, January-April 2022. A total of 56 individuals, both males and females aged 30-75 years having T2DM with fasting blood glucose ≥ 110 mg/dl and HbA1c ≥ 5.7% were included. Biochemical markers were estimated by applying standard methods. Independent sample t-test, Fisher exact test, and linear regression were applied. Results: TGI and triglyceride HDL ratio were significantly raised (p=0.01) in patients with poor glycemic control as compared to controlled glucose levels (17.8 ± 4.7vs7.3 ± 1.75) and (3.84 ± 1.3vs2.12 ± 0.64) respectively. These two indices have a significant association (p=0.01) with HbA1c (r=0.963, r=0.757), fasting blood glucose (r=0.964, r=0.748), and HOMA-IR (r=0.955, r=0.718) respectively. Moreover, TGI and THR were found to have a more significant association with the development of cardiovascular disease (CVD) (r=0.717, r=0.555) and a significant but weak association with nephropathy (r=0.385, r=0.302) respectively. Regression analysis revealed that both TGI and THR have significant predictive ability for HbA1c, fasting blood glucose, HOMA-IR and CVD (delta R Conclusions: TGI and THR have a strong association and predictive capability to identify insulin resistance and detect the development and progression of T2DM. Moreover, TGI can be more precisely used for prediction analysis as compared to THR.
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