Evidence map›Paper›PMID 37680648›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2023

Thrombotic Microangiopathy in the Renal Allograft: Results of the TMA Banff Working Group Consensus on Pathologic Diagnostic Criteria.

Marjan Afrouzian, Nicolas Kozakowski, Helen Liapis, Verena Broecker, Luon Truong, Carmen Avila-Casado, Heinz Regele, Surya Seshan, Josephine M Ambruzs, Alton Brad Farris and 17 more

Erratum issuedOpen access · goldAbstract readConsensus Statement
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Post-transplant Thrombotic Microangiopathy.Journal of the American Society of Nephrology : JASN · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Delphi: A Democratic and Cost-Effective Method of Consensus Generation in Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

27 authors at 20 institutions in 13 countries.

Marjan AfrouzianDepartment of Pathology, John Sealy School of Medicine, University of Texas Medical Branch at Galveston, Galveston, TX, United States.
Nicolas KozakowskiDepartment of Pathology, Medical University of Vienna, Vienna, Austria.
Helen LiapisDepartment of Pathology and Immunology, School of Medicine, Washington University in St. Louis, St. Louis, MO, United States.
Verena BroeckerDepartment of Clinical Pathology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Luon TruongDepartment of Pathology, The Houston Methodist Hospital, Houston, TX, United States.
Carmen Avila-CasadoLaboratory Medicine Program, University Health Network (UHN), Toronto, ON, Canada.
Heinz RegeleDepartment of Pathology, Medical University of Vienna, Vienna, Austria.
Surya SeshanDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, United States.
Josephine M AmbruzsArkana Laboratories, Little Rock, AR, United States.
Alton Brad FarrisDepartment of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, United States.
David BuobDepartment of Pathology, Université de Sorbonne, Assistance Publique-Hôpitaux de Paris, Hôpital Tenon, Paris, France.
Praveen N ChanderNew York Medical College, Valhalla, NY, United States.
Lukman CheraghvandiDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, TX, United States.
Marian C Clahsen-van GroningenDepartment of Pathology and Clinical Bioinformatics, Erasmus MC Transplant Institute, University Medical Center Rotterdam, Rotterdam, Netherlands.
Stanley de Almeida AraujoDepartamento de Parasitologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Dilek Ertoy BaydarDepartment of Pathology, School of Medicine, Koç University, Sarıyer, Türkiye.
Mark FormbyDepartment of Anatomical Pathology, NSW Health Pathology, Callaghan, NSW, Australia.
Danica Galesic LjubanovicDepartment of Pathology, School of Medicine, University of Zagreb, Zagreb, Croatia.
Loren Herrera HernandezDepartment of Pathology and Laboratory Medicine, Mayo Clinic, Rochester, MN, United States.
Eva HonsovaAeskuLab Pathology and Department of Pathology, Charles University, Prague, Czechia.
Nasreen MohamedDepartment of Pathology and Laboratory Medicine, King Fahad Specialist Hospital-Dammam, Dammam, Saudi Arabia.
Yasemin OzlukDepartment of Pathology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Türkiye.
Marion RabantDepartment of Pathology, Necker-Enfants Malades Hospital, Université Paris Cité, Paris, France.
Virginie RoyalDepartment of Pathology, Maisonneuve-Rosemont Hospital, University of Montreal, Montreal, QC, Canada.
Heather L StevensonDepartment of Pathology, John Sealy School of Medicine, University of Texas Medical Branch at Galveston, Galveston, TX, United States.
Maria Fernanda TonioloKidney Pancreas Transplantation, Instituto de Nefrología-Nephrology, Buenos Aires, Argentina.
Diana TaheriDepartment of Pathology, Isfahan Kidney Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
John Sealy Hospital · USMedical University of Vienna · ATAeskuLab (Czechia) · CZArkana Laboratories · USBaylor College of Medicine · USCornell University · USEmory University · USIsfahan University of Medical Sciences · IRIstanbul University · TRMayo Clinic in Arizona · USNetherlands Bioinformatics Centre · NLNew York Medical College · USSahlgrenska University Hospital · SEUniversidade Federal de Minas Gerais · BRUniversité de Montréal · CAUniversité Paris Cité · FRUniversity Health Network · CAUniversity of Newcastle Australia · AUUniversity of Zagreb · HRWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Banff community summoned the TMA Banff Working Group to develop minimum diagnostic criteria (MDC) and recommendations for renal transplant TMA (Tx-TMA) diagnosis, which currently lacks standardized criteria. Using the Delphi method for consensus generation, 23 nephropathologists (panelists) with >3 years of diagnostic experience with Tx-TMA were asked to list light, immunofluorescence, and electron microscopic, clinical and laboratory criteria and differential diagnoses for Tx-TMA. Delphi was modified to include 2 validations rounds with histological evaluation of whole slide images of 37 transplant biopsies (28 TMA and 9 non-TMA). Starting with 338 criteria in R1, MDC were narrowed down to 24 in R8 generating 18 pathological, 2 clinical, 4 laboratory criteria, and 8 differential diagnoses. The panelists reached a good level of agreement (70%) on 76% of the validated cases. For the first time in Banff classification, Delphi was used to reach consensus on MDC for Tx-TMA. Phase I of the study (pathology phase) will be used as a model for Phase II (nephrology phase) for consensus regarding clinical and laboratory criteria. Eventually in Phase III (consensus of the consensus groups) and the final MDC for Tx-TMA will be reported to the transplantation community.

Indexed as

Kidney TransplantationThrombotic MicroangiopathiesAllograftsAminesAnticoagulantsHumansKidneyAminesAnticoagulantsBanffDelphikidneypathology criteriathrombotic microangiopathytransplant

Identifiers

PMID37680648
PMCPMC10481335
OpenAlexW4386096593

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.