Evidence map›Paper›PMID 37680632›Full record

ReviewFrontiers in immunology2023

Factors impacting the benefits and pathogenicity of Th17 cells in the tumor microenvironment.

Jie Xing, Changfeng Man, Yingzhao Liu, Zhengdong Zhang, Huiyong Peng

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
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  12. Microenvironment-based immunotherapy in oral cancer: a comprehensive review.Medical oncology (Northwood, London, England) · 2025
    Review
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  19. The role ofTranslational cancer research · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jie XingDepartment of Laboratory Medicine, The Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Changfeng ManDepartment of Oncology, The Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Yingzhao LiuDepartment of Endocrinology, The Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Zhengdong ZhangDepartment of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China.
Huiyong PengDepartment of Laboratory Medicine, The Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Jiangsu University · CNAffiliated Hospital of Jiangsu University · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor development is closely associated with a complex tumor microenvironment, which is composed of tumor cells, blood vessels, tumor stromal cells, infiltrating immune cells, and associated effector molecules. T helper type 17 (Th17) cells, which are a subset of CD4

Indexed as

Th17 CellsTumor MicroenvironmentCell DifferentiationImmunotherapyVirulenceanti-/pro-tumormolecular regulationTh17 cellstransdifferentiationtumor microenvironment

Identifiers

PMID37680632
PMCPMC10481871
OpenAlexW4386091102

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.