Evidence map›Paper›PMID 37680102›Full record

ArticleJournal of diabetes2024

Association of visceral fat area or BMI with arterial stiffness in ideal cardiovascular health metrics among T2DM patients.

Ling Zhao, Xiangming Zhou, Yufei Chen, Qijuan Dong, Qidong Zheng, Yufan Wang, Li Li, Dong Zhao, Bangqun Ji, Fengmei Xu and 6 more

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 1 country.

Ling ZhaoDepartment of Endocrinology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Xiangming ZhouDepartment of Endocrinology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Yufei ChenDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0003-4023-2861
Qijuan DongDepartment of Endocrinology, People's Hospital of Zhengzhou Affiliated Henan University of Chinese Medicine, zhengzhou, China.
Qidong ZhengDepartment of Internal Medicine, The Second People's Hospital of Yuhuan, Yuhuan, China.
Yufan WangDepartment of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Li LiDepartment of Endocrinology, Ningbo First Hospital, Ningbo, China.
Dong ZhaoCenter for Endocrine Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-9847-5439
Bangqun JiDepartment of Endocrinology, Xingyi People's Hospital, Xingyi, China.
Fengmei XuDepartment of Endocrinology and Metabolism, Hebi Coal (group). LTD. General Hospital, Hebi, China.
Juan ShiDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0003-2652-8084
Ying PengDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0003-1069-7000
Yifei ZhangDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0003-0272-0602
Yuancheng DaiDepartment of Internal Medicine of Traditional Chinese Medicine, Sheyang Diabetes Hospital, Yancheng, China.
Tingyu KeDepartment of Endocrinology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Weiqing WangDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shanghai Jiao Tong University · CNKunming Medical University · CNAnyang Hospital of Traditional Chinese Medicine · CNBeijing Luhe Hospital Affiliated to Capital Medical University · CNHefei Design and Research Institute of Coal Industry (China) · CNNingbo First Hospital · CNYuxian People's Hospital · CNZhengzhou University · CN

Funding

Capacity building for multidisciplinary cooperation in diagnosis and treatment of major metabolic diseases Z155080000004China Health Promotion FoundationChinese Academy of Engineering 2019-XZ-42National Key Research and Development Program of China 2016YFC0901200National Key Research and Development Program of China 2018YFC1311800National Natural Science Foundation of China 82200939National Natural Science Foundation of China 82201475Program for Shanghai Outstanding Medical Academic Leader 2019LJ07Yunnan Fundamental Research Projects 202201AT070242Yunnan Science and Technology Plan Project 202201AY070001-127
6 · The paper itself

Abstract

background"Obesity paradox" occurs in type 2 diabetes mellitus (T2DM) patients when body mass index (BMI) is applied to define obesity. We examined the association of visceral fat area (VFA) as an obesity measurement with arterial stiffness in seven ideal cardiovascular health metrics (ICVHMs).

methodsA total of 29 048 patients were included in the analysis from June 2017 to April 2021 in 10 sites of National Metabolic Management Centers. ICVHMs were modified from the recommendations of the American Heart Association. Brachial-ankle pulse wave velocity (BaPWV) ≥ 1400 cm/s was employed to evaluate increased arterial stiffness. Multivariate regression models were used to compare the different effects of BMI and VFA on arterial stiffness.

resultsLower VFA was more strongly associated with low BaPWV than lower BMI when other ICVHMs were included (adjusted odds ratio [OR], 0.85 [95% confidence interval [CI], 0.80-0.90] vs OR 1.08 [95% CI, 1.00-1.17]). Multivariable-adjusted ORs for arterial stiffness were highest in patients with the VAT area VFA in the range of 150-200 cm

conclusionIn patients with T2DM, using VAT for anthropometric measures of obesity, VFA was more relevant to cardiovascular risk than BMI in the seven ICVHMs. For anthropometric measures of obesity in the ICVHMs to describe cardiovascular risk VFA would be more optimal than BMI.

Indexed as

Diabetes Mellitus, Type 2Vascular StiffnessAnkle Brachial IndexBody Mass IndexHumansIntra-Abdominal FatObesityPulse Wave AnalysisQuality Indicators, Health CareRisk Factorsarterial stiffnessideal cardiovascular health metricstype 2 diabetesvisceral fat area

Identifiers

PMID37680102
PMCPMC10809303
OpenAlexW4386530085

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.