Evidence map›Paper›PMID 37679812›Full record

ArticleCritical care (London, England)2023

Out-of-hospital cardiac arrest in children: an epidemiological study based on the German Resuscitation Registry identifying modifiable factors for return of spontaneous circulation.

Stephan Katzenschlager, Inga K Kelpanides, Patrick Ristau, Matthias Huck, Stephan Seewald, Sebastian Brenner, Florian Hoffmann, Jan Wnent, Jo Kramer-Johansen, Ingvild B M Tjelmeland and 3 more

Open access · goldAbstract read
In one paragraph

Article in Critical care (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 3 countries.

Stephan KatzenschlagerDepartment of Anaesthesiology, Heidelberg University Hospital, Im Neuenheimer Feld 420, 69120, Heidelberg, Germany. stephan.katzenschlager@med.uni-heidelberg.de.
Inga K KelpanidesDepartment of Research and Development, Division of Emergencies and Critical Care, Oslo University Hospital, Oslo, Norway.
Patrick RistauInstitute for Emergency Medicine, University Hospital Schleswig-Holstein, Kiel, Germany.
Matthias HuckDepartment of Anaesthesiology, Heidelberg University Hospital, Im Neuenheimer Feld 420, 69120, Heidelberg, Germany.
Stephan SeewaldInstitute for Emergency Medicine, University Hospital Schleswig-Holstein, Kiel, Germany.
Sebastian BrennerDepartment of Pediatric and Adolescent Medicine, University Clinic Carl Gustav Carus, Dresden, Germany.
Florian HoffmannPaediatric Intensive Care and Emergency Medicine, Dr. Von Hauner Children's Hospital, Ludwig-Maximilians-University, Munich, Germany.
Jan WnentInstitute for Emergency Medicine, University Hospital Schleswig-Holstein, Kiel, Germany.
Jo Kramer-JohansenFaculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Ingvild B M TjelmelandFaculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Markus A WeigandDepartment of Anaesthesiology, Heidelberg University Hospital, Im Neuenheimer Feld 420, 69120, Heidelberg, Germany.
Jan-Thorsten GräsnerInstitute for Emergency Medicine, University Hospital Schleswig-Holstein, Kiel, Germany.
Erik PoppDepartment of Anaesthesiology, Heidelberg University Hospital, Im Neuenheimer Feld 420, 69120, Heidelberg, Germany.
Heidelberg University · DEUniversity of Lübeck · DEUniversity of Oslo · NOLudwig-Maximilians-Universität München · DEUniversity Hospital Carl Gustav Carus · DEUniversity Hospital Heidelberg · DEUniversity Hospital Schleswig-Holstein · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis work provides an epidemiological overview of out-of-hospital cardiac arrest (OHCA) in children in Germany between 2007 and 2021. We wanted to identify modifiable factors associated with survival.

methodsData from the German Resuscitation Registry (GRR) were used, and we included patients registered between 1st January 2007 and 31st December 2021. We included children aged between > 7 days and 17 years, where cardiopulmonary resuscitation (CPR) was started, and treatment was continued by emergency medical services (EMS). Incidences and descriptive analyses are presented for the overall cohort and each age group. Multivariate binary logistic regression was performed on the whole cohort to determine the influence of (1) CPR with/without ventilation started by bystander, (2) OHCA witnessed status and (3) night-time on the outcome hospital admission with return of spontaneous circulation (ROSC).

resultsOHCA in children aged < 1 year had the highest incidence of the same age group, with 23.42 per 100 000. Overall, hypoxia was the leading presumed cause of OHCA, whereas trauma and drowning accounted for a high proportion in children aged > 1 year. Bystander-witnessed OHCA and bystander CPR rate were highest in children aged 1-4 years, with 43.9% and 62.3%, respectively. In reference to EMS-started CPR, bystander CPR with ventilation were associated with an increased odds ratio for ROSC at hospital admission after adjusting for age, sex, year of OHCA and location of OHCA.

conclusionThis study provides an epidemiological overview of OHCA in children in Germany and identifies bystander CPR with ventilation as one primary factor for survival. Trial registrations German Clinical Trial Register: DRKS00030989, December 28th 2022.

Indexed as

Out-of-Hospital Cardiac ArrestChildEpidemiologic StudiesHumansInfant, NewbornRegistriesResuscitationReturn of Spontaneous CirculationEmergency medical serviceEpidemiologyOut-of-hospital cardiac arrestPaediatric cardiac arrestResuscitation

Identifiers

PMID37679812
PMCPMC10485980
OpenAlexW4386526770

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.